Efficiency of diffusion weighted magnetic resonance in differentiation between benign and malignant endometrial lesions

The usefulness of diffusion-weighted MRI in the differentiation between focal uterine endometrial soft tissue lesions

“…These results are consistent with the results of Elsammak et al [3], who found a significant difference between the mean ADC values of malignant masses (0.82 ×10 3 mm 2 /s) and benign lesions (1.44 × 10 −3 mm 2 /s), and those of Kececi et al [12], who revealed that the mean ADC value of 42 malignant lesions (0.94 ± 0.18 × 10 −3 mm 2 /s) was statistically significantly lower than the mean ADC value of benign lesions (1.45 ± 0.22 × 10 −3 mm 2 /s) (P < 0.01), and matched also with Fujii et al [17], who concluded that malignant tumors namely endometrial carcinoma and carcinosarcoma show lower ADC values than benign tumors. Also, Thulaseedharan et al [18] and Heo et al's [19] studies showed that there was a much lower ADC value for malignant endometrial lesions compared to the benign endometrial lesions.…”

“…Our results were in harmony with Elsammak et al's [3] results which concealed that conventional MRI could correctly diagnose 36/42 cases, achieving 77.8% sensitivity, 99.17% specificity, 87.5 PPV, and 84.6% NPV, and matched also with Bharwani et al [23] who stated that the addition of DWI to conventional MRI has increased the sensitivity and specificity to 86% and 100%, respectively, in the diagnosis of uterine endometrial lesions; Takeuchi et al [24,26] reported a sensitivity and specificity of DWI in endometrial lesions which were 100% and 81%, respectively.…”

“…Our results are in agreement with those of Elsammak et al, who classified 42 lesions as benign (24 cases) and malignant (18 cases) groups according to their histopathology results and found that the most common benign lesion was endometrial hyperplasia, while the most common malignant lesion was endometrial carcinoma [3]. Additionally, Kilickesmez et al reported that endometrial carcinoma was the most common malignant endometrial lesions [11].…”

“…Endometrial and cervical carcinomas as well as uterine sarcomas are among the top list [1]. Most endometrial conditions show overlap in terms of imaging features with normal menstrual endometrial phases and variable endometrial pathologies, such as endometrial hyperplasia, polyps, submucosal fibroid, and endometrial carcinoma [2,3]. Endometrial carcinoma is considered the most common female genital malignancy and the fourth most common type of female cancer [4].…”

To Correlate the Mri Findings With That of Transvaginal Ultrasound

“…on T2WI, 26 cases (40 %) were hypointense, 5 cases (8%) were hyper intense, 23 cases (35%) were heterogenous and 11 cases (17 %) were isointense. This is in accordance with the study of Ahmed Elsammaketal in 2008 [5] which showed lesions with hypointense signals at T1WI, heterogeneous signals at T2WI were probably malignant, while those that displayed hypointense signals on T1W images, hyperintense signals on T2W images were probably benign.…”