Efficiency of Electronic Health Record Assessment of Patient-Reported Outcomes After Cancer Immunotherapy

Abstract

Key Points Question Can an electronic patient-reported outcome (ePRO) model improve outcome in cancer immunotherapy compared with a traditional model? Findings In this randomized clinical trial of 278 patients from 28 Chinese hospitals comparing ePRO and traditional follow-up models, the intervention group showed a reduced incidence of serious immune-related adverse events, fewer emergency department visits, a lower rate of treatment discontinuation, a higher quality of life, and less time needed to implement the model. Meaning These findings suggest that the ePRO follow-up model is efficient and may provide reliable information and management recommendations in patients receiving immunotherapy for cancer.

Analyzing the Effect of Telemedicine on Domains of Quality Through Facilitators and Barriers to Adoption: Systematic Review

“…This was performed to summarize the study characteristics in a manner established in the literature. Of the 33 studies analyzed, all were published over a 1-year period [ 28 - 60 ]. Only 6% (2/33) of the studies involved participants younger than 18 years [ 40 , 47 ].…”

“…For instance, the theme of improved mental health included improvements in anxiety, mental well-being, stress, loneliness, depression, fear, personal satisfaction, helplessness, rumination, acceptance, resilience, and suicidal ideation. Multimedia Appendices 1 and 2 [ 28 - 60 ] provide an observation-to-theme match for all studies. Multimedia Appendix 3 [ 28 - 60 ] provides other data fields collected during the data extraction phase of the systematic literature review.…”

“…Multimedia Appendices 1 and 2 [ 28 - 60 ] provide an observation-to-theme match for all studies. Multimedia Appendix 3 [ 28 - 60 ] provides other data fields collected during the data extraction phase of the systematic literature review.…”

“…This theme encompassed anxiety, well-being, stress, loneliness, depression, fear, personal satisfaction, helplessness, rumination, acceptance, suicidal ideation, and resilience. There were 13% (12/92) of instances of improved medical engagement [ 28 , 30 , 32 , 35 , 36 , 40 , 43 , 46 , 48 , 60 ]. This theme included medication compliance, program or treatment adherence, follow-up visits, medical knowledge, and decrease in emergency department visits.…”

“…This theme included medication compliance, program or treatment adherence, follow-up visits, medical knowledge, and decrease in emergency department visits. There were 12% (11/92) of instances of 2 themes: changed behavior, which included sexual behavior, self-care, drinking, smoking, physical activity, weight loss, and salt intake [ 29 , 32 , 34 , 50 , 53 , 55 , 56 , 58 - 60 ] and increased quality of life (QoL), which included sleep, vitality, interpersonal problems, attitude, or as measured by the EuroQoL visual analog scale [ 31 , 36 , 37 , 39 - 41 , 45 , 54 , 56 , 57 , 59 , 60 ]. There were 7% (6/92) of instances of increased self-efficacy [ 28 , 35 , 36 , 41 , 47 ].…”