Efficiency of Fetuin-A and Procalcitonin in the Diagnosis of Infection in Patients with Febrile Seizure

Al‐Hakeim, Hussein Kadhem; Al-Ankoshy, Azhar Mohammed; Alsharifi, Mohammed-R.

doi:10.1515/afmnai-2016-0004

Cited by 1 publication

(1 citation statement)

References 42 publications

(44 reference statements)

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“…A similar result was obtained by Salam OA, who observed significantly higher serum levels of CRP, IL-6 and Total WBC count in febrile patients in relation to negative control children and in FS children in comparison to FC children [24] . Al-Hakeim HK et al shown increase CRP and PCT in FS children in comparison with a healthy control group [25] . Interestingly, serum PCT levels were increased significantly in FS as compared to the healthy control group while no statistical difference between FS and FC.…”

Section: Discussionmentioning

confidence: 97%

The role of electrolytes and inflammatory biomarkers in the development of febrile seizure in children

Mhaibes¹,

Al-Anbaki²,

Saleh³

2020

ATMPH

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Febrile seizures (FS) are a prevalent type of seizure occurs due to fever in children aged between six months and five years. This study aimed to explain the effect of electrolyte disturbance in FS and the role of procalcitonin (PCT) as an inflammatory biomarker in the diagnosis of FS. The case-control study was performed at the Children Welfare Hospital, Medical City, Baghdad, Iraq, included 90 children aged six months to five years divided into 40 children with FS, 30 children were admitted to emergency department with fever a count as a febrile control (FC) group and 20 healthy children free of infection. The study involved the measurement of serum electrolyte (Na, K, and Ca) and some inflammatory biomarkers (PCT, CRP, and ESR). The data revealed no significant difference in PRO and ESR between the FS and FC while there are significantly elevated PRO and ESR in patient groups as compared to that of the healthy control group at p <0.05. The data explain that the mean level of CRP was significantly higher in FS than FC while there was no significant difference between FC and healthy control groups. Lower serum sodium in FS as compared to FC and decrease serum potassium level in FS. In conclusion, Patients with FS have higher total WBC count, ANC and serum CRP levels than the febrile control group while significantly higher serum PCT and ESR levels in FS than healthy control. Also, lower serum sodium and potassium levels in FS patients could have a role in the development of FS.

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Section: Discussionmentioning

confidence: 97%