Efficiency of separating amine 5,7-dinitrobenzofurazane derivatives

Evgen'ev, M. I.; Evgen'eva, I. I.; Levinson, F. S.; Valitova, Ya. R.

doi:10.1134/s1061934811070069

Cited by 3 publications

(5 citation statements)

References 4 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Due to the difference in the spectral parameters of the derivatives of BFZ of hydrazine and such compounds as aniline, methylhydrazine, UDMH, semicarbazide, large excesses of the latter do not interfere with the determination of hydrazine. At the same time, by the example of hydrazides of isoni cotinic, benzoic, and diphenylphosphenylacetic acid the possibility of simultaneous determination in mix tures has been demonstrated, such possibility being important for the analysis of pharmaceutical forms [55,56]. Redox reactions.…”

mentioning

confidence: 98%

“…For the same flow injection analyzer the productiv ity of UDMH determination as a 5,7 dinitrobenzo furazane derivative is 24 sample/h because of a lower solvent flow rate which was chosen as the optimal one [90]. In the flow system the absorption maximum of the derivative shifts from 450-455 nm into the wave length region 500-520 nm, such effect being associ ated with the formation of a complicated mixture of the solvents as a result of flow mixing.…”

mentioning

confidence: 99%

“…It was proposed to use BFZ for the flow injection determination of hydrazine [88], UDMH [90] and monosubsituted hydrazides [91]. The problem of hydrazine determination with BFZ is the low rate of reaction between the reagents and, consequently, low intensity of the signal for the chosen system productiv ity (46 samples/h).…”

mentioning

confidence: 99%

See 2 more Smart Citations

Spectrophotometric and fluorometric methods for the determination of hydrazine and its methylated analogues

2012

View full text Add to dashboard Cite

show abstract

mentioning

confidence: 98%

mentioning

confidence: 99%

See 1 more Smart Citation

Spectrophotometric and fluorometric methods for the determination of hydrazine and its methylated analogues

2012

View full text Add to dashboard Cite

show abstract

“…To increase the yield in the formation of 5,7 dini trofurazan derivatives of analytes, the catalytic effects of alumina and silica were utilized [7,8]. The reaction of low volatile N,N dimethylaniline and dipheny lamine with BFZ was performed on a Silufol TLC plate; the derivative formed was then eluted from the plate with acetonitrile.…”

Section: Methodsmentioning

confidence: 99%

A Passive chemical dosimeter for the determination of N-substituted aromatic amines in air

2013

Self Cite

View full text Add to dashboard Cite

Abstracts-A passive chemical dosimeter for the determination of a long exposure of N substituted aromatic amines in air is described. The analytes are accumulated on a sorption filter by the many hour exposure of a unit using a chemical reaction with a selective reagent. The diffusion coefficients, rate of chemisorption pre concentration, and detection limits of chemical dosimeters are found. The concentrations of N methyl aniline, N,N dimethylaniline, and diphenylamine in air samples are determined.

show abstract

“…These compounds are widely used in chemical technology, science, and industry for the synthesis of drugs, dyes, and antioxi dants. 4 Chloro 5,7 dinitrobenzofurazan is used as an efficient reagent for determining aromatic amines and hydrazines in air, water, and biological fluids by spec trophotometric, test, and chromatographic methods [3,4]. Therefore, it is of interest to identify factors influ encing the selectivity of the separation of 5,7 dinitroben zofurazan derivatives of aromatic amines by reversed phase high performance liquid chromatography (RP HPLC).…”

mentioning

confidence: 99%

Effect of mobile phase nature on the selectivity of separation of 5,7-dinitrobenzofurazan derivatives of amino compounds by reversed-phase HPLC

2012

Self Cite

View full text Add to dashboard Cite

728Compounds containing amino groups are among the most important classes of organic compounds and are widespread in nature [1,2]. These compounds are widely used in chemical technology, science, and industry for the synthesis of drugs, dyes, and antioxi dants. 4 Chloro 5,7 dinitrobenzofurazan is used as an efficient reagent for determining aromatic amines and hydrazines in air, water, and biological fluids by spec trophotometric, test, and chromatographic methods [3,4]. Therefore, it is of interest to identify factors influ encing the selectivity of the separation of 5,7 dinitroben zofurazan derivatives of aromatic amines by reversed phase high performance liquid chromatography (RP HPLC).The mobile phase in liquid chromatography fulfills a double function. From one hand, it serves to trans port analyte molecules along the chromatographic column; therefore, the physical properties of the sol vent, such as viscosity, volatility, etc., are important. From the other hand, the mobile phase plays an active chemical role: it interacts with the molecules of the retained substances and also with the molecules of the stationary phase, influencing the results of separation [5,6].The objective of this work was to study the nature and composition of the mobile phase effect on the selectivity of separation of 5,7 dinitrobenzofurazan derivatives of amino compounds. EXPERIMENTALIn this work, an HPLC system HP 1100 (Hewlett Packard) was used; it consisted of a four channel gra dient pump HPG1311A with a degasser HPG1322A, a Reodyne injector 5525 HPG1328A, a column ther mostat G1316A, a diode array detector HPG1315A, and a ChemStation data processing system with the G2170AA software. Separation was carried out on a Zorbax SB C 18 column (250 × 4.6 mm) protected with a Hypersil guard column ODS (50 × 4 mm). The injection volume was 20 μL. The quantitative process ing of the chromatographic data for different versions of detection was performed by chromatographic peak areas. The optimization of the separation conditions was done by 3D chromatogram images on the coordi nates time-signal intensity-wavelength.Acetonitrile and methanol of chromatographic purity (Criochrom, St. Petersburg) were used. Water of chromatographic purity was obtained using a Simplic ity 185 system.The selectivity coefficient was calculated using the equationwhere t R, 1 and t R, 2 are retention times of two compo nents, t 0 is column dead time, and t 0 = 2.48 min (determined using uracil). RESULTS AND DISCUSSIONIn chromatography, the molecules of compounds to be separated and the solvents compete for the active binding sites on the adsorbent surface [7⎯9]. In many cases, molecules of the mobile phase are adsorbed on the stationary phase surface, changing the properties of the adsorbent. Therefore, it is possible to influence the mechanism of substance retention by varying the nature and composition of the mobile phase. Often a Abstract-Selectivity coefficients of a series of 5,7 dinitrobenzofurazan derivatives of amino compounds in the separation by reversed ...

show abstract

Efficiency of separating amine 5,7-dinitrobenzofurazane derivatives

Cited by 3 publications

References 4 publications

Spectrophotometric and fluorometric methods for the determination of hydrazine and its methylated analogues

Spectrophotometric and fluorometric methods for the determination of hydrazine and its methylated analogues

A Passive chemical dosimeter for the determination of N-substituted aromatic amines in air

Effect of mobile phase nature on the selectivity of separation of 5,7-dinitrobenzofurazan derivatives of amino compounds by reversed-phase HPLC

Contact Info

Product

Resources

About