The condition of the tourism environment is the key factor that affects the tourism experience. A comprehensive evaluation of the tourism environmental suitability score is of great significance for guiding tourism planning and decision-making, improving the suitability score of the tourism environment in a targeted manner and guaranteeing the sustainable development of tourist cities. By adopting various indicators, such as the Universal Thermal Climate Index, the amount of precipitation, the vegetation index, the concentration of fine particulate matter in the atmosphere, and the ultraviolet radiation intensity index, this study quantifies the comfort level of weather, the weather impacts, the vegetation status, the atmospheric environment, ultraviolet radiation, and other key factors. Based on employing the AHP-TOPSIS algorithm, this study then conducts a comprehensive evaluation of China's tourism environmental suitability score and a comprehensive comparative analysis of the tourism environmental suitability scores of three typical tourist areas: the Beijing-Tianjin-Tangshan area, the Yangtze River Delta and the Pearl River Delta. The results show that the tourism environmental suitability score in China has obvious characteristics of spatial differentiation: the scores in East and South China are the highest while the score in the north-west inland area is the lowest. Among the three typical tourist areas, the Pearl River Delta region has the highest tourism environmental suitability score, followed by the Yangtze River Delta region, and the Beijing-Tianjin-Tangshan region has the lowest score. The northern regions of the Beijing-Tianjin-Tangshan area, the southern regions of the Yangtze River Delta and the surrounding areas of the Pearl River Delta are more suitable for the sustainable development of the tourism industry. PM2.5 is the main factor limiting the tourism environmental suitability scores in the Beijing-Tianjin-Tangshan area and the Yangtze River Delta, so atmospheric environment management will be an effective way to improve their tourism environmental suitability scores.