Background. Prevention of adhesions remains an urgent problem of abdominal surgery, despite the significant amount of research in this area. In the prevention of adhesions there are four areas: reduction of peritoneal injury; reduction of the inflammatory reaction in the area of operation; the effect of remedial drugs on the balance of formation and destruction of fibrin; delimitation of damaged serous membranes by the formation of protective films on the mesothelium.Material and methods. 84 laboratory mature white male rats, which were divided into 8 groups, were studied. The adhesion process was simulated with some groups using an anti-adhesive based on hyaluronic acid. On the 4th, 10th, and 30th day after the beginning of the experiment, the experimental animals were euthanized, the abdominal cavity was opened, and the visceral and parietal peritoneum and adhesions were examined through standard macroscopic and microscopic methods. luźna, łatwo oddzielająca się, nie zniekształcała struktury światła i prawie nie zmieniała przewodu pokarmowego.