Efficient and Eco-Friendly Synthesis of Fluorenone Azines by Using Sulphated Titania Acid Catalyst

Abstract

ABSTRACT. Conjugated unsymmetrical azines have been synthesized in the presence of acid catalyst sulphated-titania (TiO 2 -SO 4 2-) from fluorenone hydrazone with substituted aldehydes and acetophenones by using mortar and pestle. The scope of present synthetic route avoid in solvents, simple operating method and shorter reaction time. Special feature of synthetic method is recyclable catalyst for all in reactions.

Sulfated Titania (TiO2‐SO42−) as an Efficient Catalyst for Organic Synthesis: Overarching Review from 2000 to 2021

“…Henceforth, unsymmetrical azines were synthesized by condensation of fluorenone hydrazone with substituted ketones and aldehydes in the presence of an efficient catalyst TiO 2 ‐SO 4 2− (Scheme 48). [98,99] Yields are not much affected by the substituents present in the aldehydes or ketones while using TiO 2 ‐SO 4 2− .…”

“…Synthetic route for the formation of azines. [98,99] ChemistrySelect examined in the study, the catalytic conversion to LGO with high selectivity was obtained with TiO 2 -SO 4…”

“…Henceforth, unsymmetrical azines were synthesized by condensation of fluorenone hydrazone with substituted ketones and aldehydes in the presence of an efficient catalyst TiO 2 -SO 4 2À (Scheme 48). [98,99] Yields are not much affected by the substituents present in the aldehydes or ketones while using TiO 2 -SO 4 2À . Arun and Sankaran [100] have synthesized fluorenone unsymmetrical azines from the reaction of fluorenone hydrazone with biphenyl-4-carboxaldehyde and naphthaldehyde by using solid acid catalyst TiO 2 -SO 4 2À (Scheme 49).…”