Efficient disinfection of SARS-CoV-2-like coronavirus, pseudotyped SARS-CoV-2 and other coronaviruses using cold plasma induces spike protein damage

Qin, Hongbo; Qiu, Hengju; He, Shiting; Hong, Bixia; Liu, Ke; Lou, Fuxing; Li, Maochen; Hu, Pan; Kong, Xianghao; Song, Yujie; Liu, Yuchen; Pu, Mingfang; Han, Pengjun; An, Xiaoping; Song, Lihua; Tong, Yigang; Fan, Hao

doi:10.1016/j.jhazmat.2022.128414

Cited by 45 publications

(29 citation statements)

References 77 publications

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“…PAW after 30 days and room-temperature storage remained capable of largely disrupting the S protein's receptor-binding domain (RBD) interaction with the angiotensin-converting enzyme 2 (ACE2) receptor. [85] Their findings provide evidence of a potent disinfection strategy to combat the COVID-19 pandemic.…”

Section: Plasma-based Media For Sanitization and Infection Controlmentioning

confidence: 96%

Cold atmospheric plasma for addressing the COVID‐19 pandemic

Chen

Bai

Jonas

et al. 2022

Plasma Processes & Polymers

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The coronavirus disease 2019 (COVID‐19) pandemic has greatly stressed the global community, exposing vulnerabilities in the supply chains for disinfection materials, personal protective equipment, and medical resources worldwide. Disinfection methods based on cold atmospheric plasma (CAP) technologies offer an intriguing solution to many of these challenges because they are easily deployable and do not require resource‐constrained consumables or reagents needed for conventional decontamination practices. CAP technologies have shown great promise for a wide range of medical applications from wound healing and cancer treatment to sterilization methods to mitigate airborne and fomite transfer of viruses. This review engages the broader community of scientists and engineers that wish to help the medical community with the ongoing COVID‐19 pandemic by establishing methods to utilize broadly applicable CAP technologies.

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Section: Plasma-based Media For Sanitization and Infection Controlmentioning

confidence: 96%

Cold atmospheric plasma for addressing the COVID‐19 pandemic

Chen

Bai

Jonas

et al. 2022

Plasma Processes & Polymers

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Section: Figurementioning

confidence: 99%

Review of Developments in Combating COVID-19 by Vaccines, Inhibitors, Radiations, and Nonthermal Plasma

Han

Mumtaz

Srinivasan

et al. 2022

CIMB

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Global society has been highly pressured by the COVID-19 pandemic, which has exposed vulnerabilities in supply chains for disinfection products, personal protective equipment, and medical resources worldwide. It is critically necessary to find effective treatments and medications for these viral infections. This review summarizes and emphasizes critical features of recent breakthroughs in vaccines, inhibitors, radiations, and innovative nonthermal atmospheric plasma (NTAP) technologies to inactivate COVID-19. NTAP has emerged as an effective, efficient, and safe method of viral inactivation. NTAP can be used to inactivate viruses in an environmentally friendly manner, as well as activate animal and plant viruses in a variety of matrices. Researchers and engineers desire to help the medical world deal with the ongoing COVID-19 epidemic by establishing techniques that make use of widely available NTAP technologies. NTAP technology is not dependent on viral strain, and it does not necessitate months or years of research to develop specific vaccines for each novel or arising viral disease. We believe the NTAP is a highly promising technique for combating COVID-19 and other viruses. Thus, NTAP technology could be a significant breakthrough in the near future in assisting humans in combating COVID-19 infections. We hope that this review provides a platform for readers to examine the progress made in the fight against COVID-19 through the use of vaccines, inhibitors, radiation, and NTAP.

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“…CP is proved to be an efficient novel method for preventing the viral spreading of SARS‐CoV‐2 variants. Pulse power‐driven cold atmospheric plasma (CAP) has been reported to result in a potential inactivation of SARS‐CoV‐2‐like coronavirus GX_P2V, six strains of major epidemic SARS‐CoV‐2 variants and even swine coronavirus PEDV and SADS‐CoV within 300 s (Qin et al, 2022). The primary reactive species responsible for inactivation of GX_P2Vand SARS‐CoV‐2 are ONOO‐, 1 O 2 , O 2 ‐ and OH.…”

Section: Effect Of Cp On Microbial Inactivation In Foodmentioning

confidence: 99%

“…Atmospheric dielectric barrier discharge cold plasma (ADCP) is also reported to be effective in inactivating the human norovirus such as TV. Lee, Cheigh, et al, variants and even swine coronavirus PEDV and SADS-CoV within 300 s (Qin et al, 2022). The primary reactive species responsible for inactivation of GX_P2Vand SARS-CoV-2 are ONOO-, 1 O 2 , O 2and OH.…”

Section: Effect On Virusesmentioning

confidence: 99%

Effects of cold plasma on food poisoning microbes and food contaminants including toxins and allergens: A review

Kumar

Yadav

Dalbhagat

et al. 2022

Food Processing Preservation

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Cold plasma (CP) has emerged as a powerful intervention in the non‐thermal processing of food. It a green technology with a minimum negative impact on food and the environment. Though many conventional biological, chemical and thermal techniques have not given satisfactory results, CP has shown an exceptional promise in the elimination of several kinds of food contaminants including food poisoning microbes such as bacteria, fungi, and parasites, heavy metals, toxins, and allergens. CP plays an important role in the inactivation and inhibition of food poisoning microbes. It could be a befitting alternative to traditional models because of its promising results in diverse groups of food products. This review is a collation of recent studies focused on the effect of CP on various types of microbes, toxins and allergens. The review also emphasises the effect of CP on other food contaminants including the toxicity of pesticides and heavy metals. Practical applications The CP technology being a green non‐thermal process, offers numerous potential applications in food industries. With rapid advancements in plasma science, the CP technology is being widely used for surface decontamination of food products as well as food packaging materials. Several review articles are available on cold plasma processing of food products. However, none of the literature available provides a comprehensive review of effects of cold plasma on food poisoning microbes and food contaminants. The present article reviews the updated and more advanced mechanisms and new concepts about the microbial inactivation during the CP treatment. By examining the safety of gases used in CP technology, this review will help both consumers and food processors to understand the safety of the treatment and its wide‐scale commercial application in food processing.

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Efficient disinfection of SARS-CoV-2-like coronavirus, pseudotyped SARS-CoV-2 and other coronaviruses using cold plasma induces spike protein damage

Cited by 45 publications

References 77 publications

Cold atmospheric plasma for addressing the COVID‐19 pandemic

Cold atmospheric plasma for addressing the COVID‐19 pandemic

Review of Developments in Combating COVID-19 by Vaccines, Inhibitors, Radiations, and Nonthermal Plasma

Effects of cold plasma on food poisoning microbes and food contaminants including toxins and allergens: A review

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