Efficient droplet router for digital microfluidic biochip using particle swarm optimizer

Pan, Indrajit; Samanta, Tuhina

doi:10.1117/12.2012352

Cited by 6 publications

(4 citation statements)

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“…Stall and detour are also used in paper "Efficient droplet router for digital microfluidic biochip using particle swarm optimizer" to solve conflicting condition. Stall is applied when two droplets enter conflicting area [7]. Detour is applied when two droplets' paths overlap, at that time one droplet will choose an alternative road to come.…”

Section: Algorithm For Avoiding Breaking Fluid Constrictionmentioning

confidence: 99%

A Review for Droplet Routing Algorithms on Digital Microfluid Biochip

Wen

2023

ACE

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From 2019, a new kind of virus covid-19 has spread to the world and causes serious health problem on many people. With the growing spreading of virus, covid-19, there is an increasing need for developing rapid means of diagnosis for PCR uses and possibly high throughput screening to develop new drug. As a result, developing DMFB (Digital microfluid biochip) has a broad application prospect. DMFB can be used as an experimental platform to automatically conduct various kinds of biochemical tests, including PCR. It can conduct multiple tests concurrently, using only nano-liter scales reagents. With computer aided, DMFB can save people a lot of energy and resources. To finalize this automated system, we should incorporate some algorithms in it. The routing algorithms of droplets on chip is an important part of implementing the whole system. Finding a good droplet routing algorithm can reduce the time of the whole experimental procedure as well as reduce the amount of cross-contamination to increase the accuracy rate of the experiment outcome. In this paper, a brief introduction of each measure is presented. Then an estimation of their performance is conducted by using the data they attach on their paper, using their own simulator on standard bench test. Furthermore, this paper estimates their actual utility when they are practically used on hardware facility. Finally, this review ends with a discussion about the most promising research direction in the future. This paper aims to make a concise catalog of droplet routing algorithms by first decomposing them and then classifying them according to the different stages they are being used.

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Section: Algorithm For Avoiding Breaking Fluid Constrictionmentioning

confidence: 99%

A Review for Droplet Routing Algorithms on Digital Microfluid Biochip

Wen

2023

ACE

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“…The routing algorithm presented in this paper is compatible with direct addressing [17] and active-matrix [9,15] DMFBs, which provide independent control over all electrodes; compilation flows targeting these devices are mature [1,3,11,16,18,[20][21][22]25]. It is not compatible with pin-constrained [2] and cross-referencing [6,24] DMFBs, which provide more restricted forms of control.…”

Section: Related Workmentioning

confidence: 99%

“…The vast majority of routers that have been published, to date, are polynomial-time heuristics which cannot guarantee optimality; exceptions include optimal algorithms based on A* search [1] and integer linear programming [24], and a recent iterative improvement algorithm based on particle swarm optimization [16].…”

Section: Related Workmentioning

confidence: 99%

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Exploring speed and energy tradeoffs in droplet transport for digital microfluidic biochips

Fiske

Grissom

Brisk

2014

2014 19th Asia and South Pacific Design Automation Conference (ASP-DAC)

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-This paper transforms the problem of droplet routing for digital microfluidic biochips (DMFBs) from the discrete into the continuous domain, based on the observation that droplet transport velocity is a function of the actuation voltage applied to electrodes that control the devices. A new formulation of the DMFB droplet routing problem is introduced for the continuous domain, which attempts to minimize total energy consumption while meeting a timing constraint. Henceforth, DMFBs should be viewed as continuous, highly integrated cyber-physical systems that interact with and manipulate physical quantities, as opposed to inherently discrete and fully synchronized devices.

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Weighted Optimization of Various Parameters for Droplet Routing in Digital Microfluidic Biochips

Pan¹,

Samanta

2014

Advances in Intelligent Systems and Computing

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Efficient droplet router for digital microfluidic biochip using particle swarm optimizer

Cited by 6 publications

References 0 publications

A Review for Droplet Routing Algorithms on Digital Microfluid Biochip

A Review for Droplet Routing Algorithms on Digital Microfluid Biochip

Exploring speed and energy tradeoffs in droplet transport for digital microfluidic biochips

Weighted Optimization of Various Parameters for Droplet Routing in Digital Microfluidic Biochips

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