Efficient in vitro delivery of paclitaxel by a nanocellulose-coated dendritic mesoporous organosilica nanoparticle for enhanced chemodynamic cancer therapy

Xing, Rui; Ning, Like; Li, Lan; He, Lingxiao; Lin, Haiping; You, Chaoqun; Wang, Fei

doi:10.1016/j.jddst.2023.104654

Cited by 8 publications

(2 citation statements)

References 47 publications

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“…Among the inorganic nanomaterials, porous silica nanoparticles possess inherent advantages such as colloidal stability and high loading capacity, making them highly attractive in the design of intelligent drug delivery systems due to their surface functionalization ability. − Gao et al developed a novel pesticide formulation (PYR-HMS-HPC) using mesoporous silica (HMS), and hydroxypropyl cellulose (HPC) was employed as the capping agent (Figure D). The findings demonstrated that the drug carrier exhibited significant enhancement in photodegradation resistance of pesticide molecules compared to commercial pyraclostrobin (PYR), along with improved bactericidal activity and reduced genotoxicity.…”

Section: Formation Of Cellulose-based Nanopesticidesmentioning

confidence: 99%

Advances in the Design of Functional Cellulose Based Nanopesticide Delivery Systems

You,

Lin,

Ning

et al. 2024

J. Agric. Food Chem.

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The advancement of science and technology, coupled with the growing environmental consciousness among individuals, has led to a shift in pesticide development from traditional methods characterized by inefficiency and misuse toward a more sustainable and eco-friendly approach. Cellulose, as the most abundant natural renewable resource, has opened up a new avenue in the field of biobased drug carriers by developing cellulose-based drug delivery systems. These systems offer unique advantages in terms of deposition rate enhancement, modification facilitation, and environmental impact reduction when designing nanopesticides. Consequently, their application in the field of nanoscale pesticides has gained widespread recognition. The present study provides a comprehensive review of cellulose modification methods, carrier types for cellulose-based nanopesticides delivery systems (CPDS), and various stimulus-response factors influencing pesticide release. Additionally, the main challenges in the design and application of CPDS are summarized, highlighting the immense potential of cellulose-based materials in the field of nanopesticides.

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Section: Formation Of Cellulose-based Nanopesticidesmentioning

confidence: 99%

Advances in the Design of Functional Cellulose Based Nanopesticide Delivery Systems

You,

Lin,

Ning

et al. 2024

J. Agric. Food Chem.

Self Cite

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“…The advantages of a wider application of cellulose-based materials as a new type of absorbents or fillers are related to their abundance, low cost, easy recycling, and biocompatibility. These properties are of special interest for application in different practical fields such as environmental protection [1,2], energy storage [3], garment design [4], surgical pads [5], wound healing [6][7][8], absorbent hygiene products [9], pharmaceuticals [10][11][12], and 3D printing [13]. Cellulose-based gels are also studied as future materials for food packaging and plant agriculture [14], antimicrobial [15], and electroactive [16] materials.…”

Section: Introductionmentioning

confidence: 99%

A Polyelectrolyte Colloidal Brush Based on Cellulose: Perspectives for Future Applications

Smirnov,

Vorobiov,

Fedotova

et al. 2023

Polymers

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This feature article is devoted to the evaluation of different techniques for producing colloidal polyelectrolyte brushes (CPEBs) based on cellulose nanofibers modified with grafted polyacrylates. The paper also reviews the potential applications of these CPEBs in designing electrode materials and as reinforcing additives. Additionally, we discuss our own perspectives on investigating composites with CPEBs. Herein, polyacrylic acid (PAA) was grafted onto the surface of cellulose nanofibers (CNFs) employing a “grafting from” approach. The effect of the PAA shell on the morphological structure of a composite with polypyrrole (PPy) was investigated. The performance of as-obtained CNF-PAA/PPy as organic electrode material for supercapacitors was examined. Furthermore, this research highlights the ability of CNF-PAA filler to act as an additional crosslinker forming a physical sub-network due to the hydrogen bond interaction inside chemically crosslinked polyacrylamide (PAAm) hydrogels. The enhancement of the mechanical properties of the material with a concomitant decrease in its swelling ratio compared to a pristine PAAm hydrogel was observed. The findings were compared with the recent theoretical foundation pertaining to other similar materials.

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Polymers Facilitating Therapeutic Efficacy and Applications for Traditional Chinese Medicine

Li,

Luo,

Feng

et al. 2024

Journal of Polymer Science

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The active ingredients from traditional Chinese medicine (TCM) are fundamental to its therapeutic efficacy. However, their difficult detection, low solubility, poor stability, uncertain biocompatibility, and inefficient absorption rate, hinder their clinical application. Polymers have emerged as a viable solution to these issues, providing a platform for the detection, enrichment, and exertion of pharmacological effects. This review delves into the application of polymers in active ingredients from TCM, covering various aspects including molecularly imprinted polymers (MIPs), polymer micelles, polymer hydrogels, conjugated polymers, and polymer nanoparticles (NPs). These advanced systems leverage the designability, adjustable solubility, and biocompatibility of polymers to enhance the therapeutic potential of TCM. The review concludes by discussing the current challenges and prospects of using polymers in TCM. It aims to provide a comprehensive understanding of the field, highlighting the potential of polymers to revolutionize TCM practices and contribute to the modernization of TCM.

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Efficient in vitro delivery of paclitaxel by a nanocellulose-coated dendritic mesoporous organosilica nanoparticle for enhanced chemodynamic cancer therapy

Cited by 8 publications

References 47 publications

Advances in the Design of Functional Cellulose Based Nanopesticide Delivery Systems

Advances in the Design of Functional Cellulose Based Nanopesticide Delivery Systems

A Polyelectrolyte Colloidal Brush Based on Cellulose: Perspectives for Future Applications

Polymers Facilitating Therapeutic Efficacy and Applications for Traditional Chinese Medicine

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