We describe how the couplings in an asynchronous kinetic Ising model can be inferred. We consider two cases: one in which we know both the spin history and the update times and one in which we know only the spin history. For the first case, we show that one can average over all possible choices of update times to obtain a learning rule that depends only on spin correlations and can also be derived from the equations of motion for the correlations. For the second case, the same rule can be derived within a further decoupling approximation. We study all methods numerically for fully asymmetric SherringtonKirkpatrick models, varying the data length, system size, temperature, and external field. Good convergence is observed in accordance with the theoretical expectations. Introduction.-Inferring interactions between the elements of a network can be posed as an inverse problem in statistical physics in terms of either equilibrium models [1][2][3] or nonequilibrium ones. The latter has recently gained a lot of attention because of the wider generality and relevance to systems where one has data on the system over time [4,5].In this connection, the asynchronous kinetic Ising model offers a powerful platform for theoretical insight and practical applications. Under detailed balance (symmetric couplings), it converges to the celebrated maximum entropy equilibrium Ising distribution [6]; that is, the asynchronous model includes as a subclass the Gibbs equilibrium Ising model. In many recent works, this equilibrium model is used for inferring functional connectivity and building statistical descriptions, e.g., for neuronal spike trains [2]. However, spike trains and many other real life data come in the form of time series. Since it is only under strict detailed balance that the asynchronous Ising model converges to the equilibrium Ising distribution, it is important to find the relation between the couplings found from the asynchronous model and those from the equilibrium Gibbs distribution. This becomes particularly important for analyzing data using fine time bins at which temporal correlations become important.The asynchronous Ising model is also important from another perspective. Most of the work on the subject so far has focused on models with only one type of stochastic variables. The asynchronous Ising model, however, can be viewed as a doubly stochastic model where, in addition to spin configurations, the update times of the spins are themselves stochastic variables. This differs from the