Org. Biomol. Chem.
 2024
DOI: 10.1039/d4ob00704b
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Efficient one-step amide formation using amino porphyrins

Kyle D. W. Vollett,
Hai-Ling Margaret Cheng

Abstract: A fast, high-yield one-step reaction is proposed for conjugating an MRI contrast agent to carboxylic acids and is demonstrated for synthesizing a blood-pool contrast agent that reversibly binds to albumin for in vivo vascular MRI.

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