Efficient optical resolution of water-soluble self-assembled tetrahedral M₄L₆ cages with 1,1′-bi-2-naphthol

Abstract

In this paper, a water-soluble racemic self-assembled tetrahedral cage [Fe4L6](4-) was successfully resolved into their ΔΔΔΔ and ΛΛΛΛ enantiomers by (R)-/(S)-1,1'-bi-2-naphthol. The enantiomeric excess of the resolved Fe(II) cage was 99%.

Syntheses and Structural Studies of a Series of Ti4(embonate)6-based Complexes

“…由于它在分子识别、仿生催化和药物传输等 方面具有诱人的应用前景, 最近十几年, 引起了科学家 们广泛地关注 [6][7][8][9][10][11][12] . 但目前构筑金属有机笼的金属中心 大多数集中在 Cu [13,14] 、Zn [15,16] 、Co [17,18] 、Fe [19][20][21] 、Ln(稀 土) [22,23] 、Pd [24][25][26] 和 Pt [27,28] 等, 相比之下, 人们对钛-有机 笼的研究, 相对较少. 1998 和 2005 年, Ramond 等 [29,30] 首次利用二齿和三齿的多羟基配体和 Ti(IV)离子反应, 分别合成了两例阴离子型的钛-有机四面体笼.…”

Chiral 3D Coordination Polymers Consisting of Achiral Terpyridyl Precursors: from Spontaneous Resolution to Enantioenriched Induction

“…Through the SXRD analysis, the products by adding d-o rl-CSA crystallise in the same space group F222. Althought he Flack parameters for 1b-P ranging from 0.163(15)t o0 .185(17) and those for 1b-M from 0.068(15) to 0.093 (16), the chiral preference of helical motifs in 1b-P and 1b-M can still be identified. In Figure S5, the coordination geometry of metal centres and helical motifs in 1b are similar to those of with 1a.T he different space groups of 1b and 1a may be caused by the slight change of dihedrala ngle between the part of phenyla nd tpy.…”

“…In order to explore the chiral induction effect of CSA, five randomly picked crystalso f1b-P and that of 1b-M are selected for SXRD analy-sis, respectively.T he refinement parameters are listed in the Ta ble S4 in the Supporting Information. Althought he Flack parameters for 1b-P ranging from 0.163(15)t o0 .185(17) and those for 1b-M from 0.068(15) to 0.093 (16), the chiral preference of helical motifs in 1b-P and 1b-M can still be identified. All five random crystals of 1b-P comprise ar ight-handed2 1 helical substructurea nd 1b-M has al eft-handed one.…”

“…[13] Spontaneousr esolution can result in CCPs for each single crystal,b ut the bulk products generally tend to form the conglomerate, except in some symmetry-breaking instances, [14] and the crystallising procedure remains elusive and uncontrollable. [15] Unlike soluble racemic metal-organic architectures, [16] conglomerate CCPs are essentially insoluble and cannote asy to be separated after the formation of final products. Therefore, the bulk chiral products of CCPs with homochirality or enantiomeric excess have been obtained through in situ chiral induction during the self-assembly processes.…”

Coordination Assembly of the Water‐Soluble Ti4(embonate)6 Cages with Mn2+ Ions

“…[3][4][5][6][7] Up to now, the search for novel MOCs has driven the exploration of different geometries. [8][9][10][11][12][13] Among which, the tetrahedra (M 4 L 4 and M 4 L 6 ) as the simplest polyhedral have been increasingly developed, and many tetrahedral cages constructed from different metals centers have been synthesized, including Pd, [14][15][16] Pt, [17][18] Fe, [19][20][21] Zn, [22][23] Co [24][25] and lanthanides. [26][27] However, polynucleartitanium cages (PTCs) are still rarely reported.…”