It is currently believed that there is no experimental evidence on possibly quantum features of gravity or gravity-motivated modifications of quantum mechanics. Here we show that single-atom interference experiments achieving large spatial superpositions can rule out a framework where the Newtonian gravitational interaction is fundamentally classical in the information-theoretic sense: it cannot convey entanglement. Specifically, in this framework gravity acts pairwise between massive particles as classical channels, which effectively induce approximately Newtonian forces between the masses. The experiments indicate that if gravity does reduce to the pairwise Newtonian interaction between atoms at the low energies, this interaction cannot arise from the exchange of just classical information, and in principle has the capacity to create entanglement. We clarify that, contrary to current belief, the classical-channel description of gravity differs from the model of Diosi and Penrose, which is not constrained by the same data.