2004
DOI: 10.1007/s11904-004-0026-7
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Efforts to control sexually transmitted infections as a means to limit HIV transmission: What is the evidence?

Abstract: There is overwhelming and compelling evidence that control efforts for STI have a major role to play in the prevention of HIV transmission. Community-based randomized controlled trials are set as the highest standard of evidence for showing the efficacy of STI interventions to prevent HIV transmission. The negative results of recent randomized controlled trials have cast doubt on the positive findings of the Mwanza study. Deeper analysis of the result of these trials has improved understanding of the role of S… Show more

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Cited by 8 publications
(8 citation statements)
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“…We found an increase in syphilis prevalence among waria in Jakarta from 19.3% in 2002 to 25.2% in 2007 [3]. Syphilis control needs to be emphasized as syphilis fuels the HIV epidemic by increasing susceptibility for HIV and by increasing HIV infectiousness among those already infected with HIV [8]. In addition, untreated syphilis results in short-term (e.g., genital lesions, lymphadenopathy, and alopecia) and long-term (cardiovascular complications such as aortic aneurysm and neurological complications such as meningitis) morbidity [9].…”
Section: Discussionmentioning
confidence: 80%
See 1 more Smart Citation
“…We found an increase in syphilis prevalence among waria in Jakarta from 19.3% in 2002 to 25.2% in 2007 [3]. Syphilis control needs to be emphasized as syphilis fuels the HIV epidemic by increasing susceptibility for HIV and by increasing HIV infectiousness among those already infected with HIV [8]. In addition, untreated syphilis results in short-term (e.g., genital lesions, lymphadenopathy, and alopecia) and long-term (cardiovascular complications such as aortic aneurysm and neurological complications such as meningitis) morbidity [9].…”
Section: Discussionmentioning
confidence: 80%
“…Syphilis and rectal STIs were associated with HIV infection in our study. As previous studies have indicated that these infections may result in increased risk of HIV transmission [8], it seems appropriate to focus on controlling STIs among waria in order to decrease HIV transmission. We have shown previously that periodic presumptive treatment for gonorrhea and chlamydia among female sex workers in Indonesia resulted in a rapid decline in prevalence of gonorrhea and Chlamydia [12].…”
Section: Discussionmentioning
confidence: 99%
“…1 With the epidemic of HIV, control of STDs has received higher priority throughout the world. 2 STD are the facilitating cofactor that contributes to the spread of HIV by increasing risk of infectiousness and susceptibility. 3 Empirical evidence has indicated that control of STDs can be an effective strategy of HIV prevention.…”
Section: Introductionmentioning
confidence: 99%
“…To design effective prevention interventions, we need a better understanding of how these factors shape sexual protection behavior among seropositive gay men. Prevention with HIV-positive individuals (''positive prevention'') in HIV care settings is relevant for a number of reasons: unprotected sexual activity may lead to deteriorated health through additional STIs (Dallabetta & Neilsen, 2007) or infection with treatment resistant HIV-strains and subsequent treatment failure (Remien et al, 2007;Richman et al, 2004). ''Positive prevention''is also an important contribution towards reducing onwards HIV infections.…”
Section: Introductionmentioning
confidence: 99%