Eficácia Do Uso De Corticosteroide Sistêmico No Tratamento Do Pênfigo Vulgar Oral

Abstract

Con lito de interesses:Não Contribuição dos autores: VYNF concepção, planejamento e elaboração do manuscrito. TCL concepção, planejamento e elaboração do manuscrito. LPL orientação e planejamento do manuscrito. MABN planejamento e obtenção de dados importantes para elaboração do manuscrito. LBS orientação e obtenção de dados importantes para elaboração do manuscrito. PRFB orientação, planejamento e revisão. Contato para correspondência: AbstractIntroduction: Pemphigus vulgaris is an autoimmune disease characterized by ulcerative and bullous lesions on skin and mucous membranes. The aim of this paper is to report a case of oral pemphigus vulgaris, emphasizing the treatment and discuss some clinical and histopathologic features of this disease. Case Report: The patient is a 38-year-old male, feodermic, who was referred to a specialized service in oral diagnosis in the city of João Pessoa -Paraíba State, complains of multiple ulcerative lesions in the oral cavity, dysphagia, dysphonia, and marked weight loss. The diagnostic hypotheses were pemphigus vulgaris and mucous membrane pemphigoid. An incisional biopsy was performed on buccal mucosa and the diagnosis of the pemphigus vulgaris was made. Initially, the treatment of choice was systemic administration of prednisone 80 mg. In the first weeks, a remission of the oral lesions occurred. The dosage was gradually reduced to the current dose of 2.5 mg/day. Conclusion: Treatment was effective, once there was remission of all oral lesions.

Intervenção Dietoterápica No Tratamento De Pênfigo Vulgar: Relato De Caso

“…This medicine may cause diabetes mellitus, osteoporosis, changes in mood and ulceration in the gastrointestinal tract, among others. 5 The increasing number of cases of Pemphigus Vulgaris, and in view of the importance of diet therapy of many diseases, including autoimmune diseases, shows the importance of nutrition therapy in patients with PV, adjusting their diet not only to the specific pathology, but to symptoms they may develop due to medications used for their therapy.…”

Assistência multidisciplinar no acompanhamento de pacientes com pênfigo vulgar

“…Drogas imunorreguladoras e corticosteróides tópicos (como o Propionato de Clobetasol) também podem ser utilizados na terapêutica. Além disso, é de fundamental importância o tratamento multidisciplinar, envolvendo médico, estomatologista e psicológico, devido à complexidade da doença e efeitos adversos da terapia, bem como retornos periódicos para avaliação da evolução dos pacientes 5 .…”