Eficacia y seguridad del sildenafilo en pacientes con disfunción eréctil e hipertensión arterial. Factores pronósticos de respuesta

Salom, M. Gil; Hernández, F. Pastor; Fort, R. Villamón; Sisamón, F. García

doi:10.1016/s0025-7753(02)73390-3

Cited by 5 publications

(2 citation statements)

References 26 publications

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“…Hence we had to give up on a placebo for Yidiyin, as is common in the study of the decoctions in traditional Chinese medicine. Additionally, we did not design an inhibitor of PDE5 for Yidiyin as a control trial in the animal experiment either, because the drug is not completely effective for diabetic ED, 13,14) and was not chosen as a treatment for human patients in our clinical trial. In view of insulin deficiency in the diabetic ED rats, we also used insulin (Glargine) as a substitute for Metformin or Gliguidone.…”

Section: Discussionmentioning

confidence: 99%

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Yidiyin, a Chinese Herbal Decoction, Improves Erectile Dysfunction in Diabetic Patients and Rats through the NO-cGMP Pathway

Feng¹,

Can-bin²,

Leng³

et al. 2012

Bioscience, Biotechnology, and Biochemistry

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Section: Discussionmentioning

confidence: 99%

“…11,12) Moreover, quite a number of diabetic ED patients and diabetic rats show a poor response to PDE5 inhibitor therapy. 13,14) Hence the utilization of drugs is sharply limited, especially for patients with angiocardiopathy.…”

mentioning

confidence: 99%

Yidiyin, a Chinese Herbal Decoction, Improves Erectile Dysfunction in Diabetic Patients and Rats through the NO-cGMP Pathway

Feng¹,

Can-bin²,

Leng³

et al. 2012

Bioscience, Biotechnology, and Biochemistry

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Current Awareness: Pharmacoepidemiology and Drug Safety

2003

Pharmacoepidemiology and Drug

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In order to keep subscribers up‐to‐date with the latest developments in their field, John Wiley & Sons are providing a current awareness service in each issue of the journal. The bibliography contains newly published material in the field of pharmacoepidemiology and drug safety. Each bibliography is divided into 19 sections: 1 Books, Reviews & Symposia; 2 General; 3 Anti‐infective Agents; 4 Cardiovascular System Agents; 5 CNS Depressive Agents; 6 Non‐steroidal Anti‐inflammatory Agents; 7 CNS Agents; 8 Anti‐neoplastic Agents; 9 Haematological Agents; 10 Neuroregulator‐Blocking Agents; 11 Dermatological Agents; 12 Immunosuppressive Agents; 13 Autonomic Agents; 14 Respiratory System Agents; 15 Neuromuscular Agents; 16 Reproductive System Agents; 17 Gastrointestinal System Agents; 18 Anti‐inflammatory Agents ‐ Steroidal; 19 Others. Within each section, articles are listed in alphabetical order with respect to author. If, in the preceding period, no publications are located relevant to any one of these headings, that section will be omitted.

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Pericytes, an overlooked player in vascular pathobiology

Ferland-McCollough

Slater

Richard

et al. 2017

Pharmacology & Therapeutics

195

152

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Pericytes are a heterogeneous population of cells located in the blood vessel wall. They were first identified in the 19th century by Rouget, however their biological role and potential for drug targeting have taken time to be recognised. Isolation of pericytes from several different tissues has allowed a better phenotypic and functional characterization. These findings revealed a tissue-specific, multi-functional group of cells with multilineage potential. Given this emerging evidence, pericytes have acquired specific roles in pathobiological events in vascular diseases. In this review article, we will provide a compelling overview of the main diseases in which pericytes are involved, from well-established mechanisms to the latest findings. Pericyte involvement in diabetes and cancer will be discussed extensively. In the last part of the article we will review therapeutic approaches for these diseases in light of the recently acquired knowledge. To unravel pericyte-related vascular pathobiological events is pivotal not only for more tailored treatments of disease but also to establish pericytes as a therapeutic tool.

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Eficacia y seguridad del sildenafilo en pacientes con disfunción eréctil e hipertensión arterial. Factores pronósticos de respuesta

Cited by 5 publications

References 26 publications

Yidiyin, a Chinese Herbal Decoction, Improves Erectile Dysfunction in Diabetic Patients and Rats through the NO-cGMP Pathway

Yidiyin, a Chinese Herbal Decoction, Improves Erectile Dysfunction in Diabetic Patients and Rats through the NO-cGMP Pathway

Current Awareness: Pharmacoepidemiology and Drug Safety

Pericytes, an overlooked player in vascular pathobiology

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