Egg Transport in Ovariectomized Rabbits as Affected by Different Combinations of Oestrogen and Progesterone

El-Banna, Amin A.; Sacher, Bernhard

doi:10.1677/joe.0.0680331

Cited by 7 publications

(2 citation statements)

References 18 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, when comparing PTS in the ipsilateral ampullae of COD cows with control cows, it became obvious that cows with luteal cysts revealed significantly decreased PTS as compared with controls. It is possible that decreased (El-Banna & Sacher, 1976). However, previous reports of systemic serum progesterone levels are similar in diestrus cows (10-11 ng/ml) and cows with luteal cysts (8-9 ng/ml) (Brodzki et al, 2019).…”

Section: Discussionmentioning

confidence: 83%

Cystic ovary disease impairs transport speed, smooth muscle contraction, and epithelial ion transport in the bovine oviduct

Scully

Campion

McCartney

et al. 2021

Molecular Reproduction Devel

View full text Add to dashboard Cite

Cystic ovary disease (COD) is a common cause of bovine infertility but the impact of this disease on the oviduct is unknown. The aim of this study was to analyze the effects of COD on particle transport speed (PTS), ciliary beat frequency, myosalpinx contraction, and epithelial ion transport. Oviducts were obtained from cows affected by COD and compared with those of healthy, mid-diestrus cows. PTS and CBF were examined using live-cell imaging. Smooth muscle contraction and epithelial ion transport were investigated using organ baths and Ussing chambers. Our results showed that muscarinic receptors are involved in cholinergic signaling in the oviduct and that forskolin-induced cyclic AMP production is involved in active ion transport in the oviductal epithelium. Oviducts from cows with luteal cysts revealed significantly decreased PTS (p = 0.02). Further to that, in the oviducts of COD cows, the cholinergic regulation of smooth muscle contractions and active epithelial ion transport were significantly diminished (p < 0.0001). These results imply that in COD cows, oviductal transport is compromised by decreased fluid flow speed and reduced cholinergic regulation of smooth muscle contraction and ion transport. This knowledge contributes to a more comprehensive understanding of COD supporting the development of novel therapeutic concepts for infertility treatment.

show abstract

Section: Discussionmentioning

confidence: 83%

Cystic ovary disease impairs transport speed, smooth muscle contraction, and epithelial ion transport in the bovine oviduct

Scully

Campion

McCartney

et al. 2021

Molecular Reproduction Devel

View full text Add to dashboard Cite

show abstract

“…Previous reports have shown that oocytes are transported very slowly through the isthmus as long as progesterone (P4) is the dominant hormone, and that a surge of E2 is required to modify the action of P4 and accelerate the transport of oocytes to the uterus. 35) Moreover, E2 reportedly stimulates myometrium contractility in nonpregnant humans. 36) The highest E2 concentration is observed during the follicular phase, and P4 increases in bovine oviducts after ovulation.…”

Section: Discussionmentioning

confidence: 99%

A Chinese Medicine, Tokishakuyakusan, Increases Bovine Oviductal Tonus <i>via</i> G Protein-Coupled Estrogen Receptor 1

Kubota

Yamamoto

Kimura

2022

Biological & Pharmaceutical Bulletin

View full text Add to dashboard Cite

Early embryo and sperm transport through the oviductal isthmus depends on the contraction and relaxation of the smooth muscle layers. Dysfunction of the oviduct transport is considered to be one of the causes of infertility. For human infertility, Chinese medicine is used in East Asia. Although there are many clinical reports regarding Tokishakuyakusan (TSS), there is little scientific evidence that it affects infertility. In this study, we investigated the effect of TSS on bovine oviductal contraction and relaxation via the G protein-coupled estrogen receptor 1 (GPER1). We collected bovine oviductal isthmic tissues at four stages of the estrous cycle, classified based on a macroscopic observation of the ovary. The Magnus method was used to monitor longitudinal contractility (frequency, contraction force, and tonus). The effects of TSS solution, GPER1 agonist (G-1), and antagonist (G-15) on oviductal contractility were examined. The protein expression level of GPER1 in the oviductal isthmic smooth muscle of each estrous stage was assessed by Western blotting. Although TSS did not affect frequency and contraction force, the tonus was significantly increased by TSS or G-1 at all stages ( p < 0.05), and the effect was especially highest at days 1-4 after ovulation. The addition of G-15 significantly suppressed the TSS-induced increase of oviductal tonus at all stages (p < 0.05). There was no significant difference in GPER1 protein expression among the estrous stages. TSS affects oviductal contractility by increasing tonus via GPER1, and it may accelerate gamete and early embryo transport by contracting the oviducts longitudinally.

show abstract

Motility of the female genital tract and egg transfer in cattle

Ruckebusch

1977

Vet Res Commun

View full text Add to dashboard Cite

Techniques of gonadotrophin-induoed superovulation and transfer of fertilised eggs, placing one egg in each horn of the uterus, are used to increase reproduction rate and thus the rate of genetic improvement in cattle. The motility of the ovary, the oviducts and the uterus is modified by synchronisation of oestrus in recipient cows and superovulation in donors, as well as during transfer of fertilised eggs. Better understanding of the nature of the variations in motility of the genital tract and the factors controlling it seem indispensable to reduction of the chances of failure. -double annual genetic progress in upgrading stock (Land and Hill, 1975); -achieve 70% incidence of twin calvings (Rowson et al., 1971). ~!otility of the uterus, the oviduct and the ovary is not. often cited as a common cause of failure of this technique (Foote and Onuma, 1970;Gordon, 1975). Yet that motility is a direct effect of the hormone treatment applied to bring about superovulation and synchronisation of oestrus * This article was originally written in French. Copies of the French version may be obtained free of charge by ~iting to: ~h-. J. Rodesch, Commission of the European Communities, DG XIII, B~timent Jean Monnet, Rue Alcide de Gasperi, Kirchberg, Luxembourg.

show abstract

Egg Transport in Ovariectomized Rabbits as Affected by Different Combinations of Oestrogen and Progesterone

Cited by 7 publications

References 18 publications

Cystic ovary disease impairs transport speed, smooth muscle contraction, and epithelial ion transport in the bovine oviduct

Cystic ovary disease impairs transport speed, smooth muscle contraction, and epithelial ion transport in the bovine oviduct

A Chinese Medicine, Tokishakuyakusan, Increases Bovine Oviductal Tonus <i>via</i> G Protein-Coupled Estrogen Receptor 1

Motility of the female genital tract and egg transfer in cattle

Contact Info

Product

Resources

About