Egg yolk phosphatidylcholine: Extraction, purification and its potential neuroprotective effect on PC12 cells

Chen, Jin; Lin, Songyi; Sun, Na; Bao, Zhijie; Shen, Jiaying; Lu, Xueqi

doi:10.1016/j.jff.2019.03.037

Cited by 22 publications

(23 citation statements)

References 41 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…It is well‐known that phospholipids (PLs) and choline are essential for nervous system's structural and functional integrity (Chen et al., 2019; Xiao et al., 2020). Egg yolk is just a valuable source of PLs and choline (Sun et al., 2018; Xiao et al., 2020).…”

Section: Egg's Nutrient Compositionmentioning

confidence: 99%

Egg consumption and health effects: A narrative review

Şanlıer¹,

Üstün²

2021

Journal of Food Science

View full text Add to dashboard Cite

This study was planned and conducted to investigate the effects of egg consumption on metabolic syndrome components and potential mechanisms of action on humans. Egg, an important source of animal protein, is defined as a functional food containing various bioactive compounds that can affect the proinflammatory and anti-inflammatory pathways. As a matter of fact, the egg can show immunomodulatory, anti-inflammatory, antioxidant, anticancer, or antihypertensive effects with its bioactive components. It is claimed that egg consumption may protect individuals against metabolic syndrome by increasing HDL-C levels and reducing inflammation. The increase in egg consumption creates the perception that it may lead to cardiovascular diseases due to its cholesterol content. However, there is insufficient evidence as to whether dietary cholesterol-lowers LDL-C. The possible potential mechanisms of egg impact on human health, MEDLINE, Embase, the Cochrane Central, www.ClinicalTrials. gov, PubMed, Science Direct, Google Scholar, and selected websites including) and databases were examined in this regard. With a view to delving into the rather mysterious relationship between egg cholesterol and blood cholesterol, it is necessary to understand the absorption of cholesterol from the egg and to know the functioning of the intestinal microbiota. Studies conducted to date have generally yielded inconsistent results regarding egg consumption and risks of CVD, diabetes, and metabolic syndrome.

show abstract

Section: Egg's Nutrient Compositionmentioning

confidence: 99%

Egg consumption and health effects: A narrative review

Şanlıer¹,

Üstün²

2021

Journal of Food Science

View full text Add to dashboard Cite

show abstract

“…Differing from palmitic acid with saturated double bonds, OA and LA are unsaturated fatty acids with superior healthy benefits in various aspects. , In addition to these three FAs, many other bioactive fatty acids can also be found in egg yolk, such as arachidonic acid (AA) and DHA . Unsaturated fatty acids commonly include the following functions: (1) Enhancing antioxidant capacity: The presence of fatty acid side chains can enhance the antioxidant capacity of egg-derived phospholipids and HDLs, with the specific details mentioned in the following statement. (2) Forming membrane lipids and regulating membrane-dependent progression: When the cells are stimulated, AA is released from the cell membrane and then converted a series of pro-inflammatory mediators .…”

Section: Biological Activities Of Fatty Acidsmentioning

confidence: 99%

“…Previous studies have shown that intakes of EY may increase the risks of CVDs ascribed to high levels of cholesterol and saturated fatty acids, resulting in supplement deficiency for consumers . Anyway, recent reports indicate that there is no association between proper intakes of eggs in healthy people and CVDs. , On the contrary, EY and its components possess numerous physiological benefits, particularly regarding anti-inflammatory, antimicrobial, and antioxidant activities, protecting eyesight, and improving memory. ,− It is well-known that phospholipids (PLs) and choline are essential for nervous system structural and functional integrity . EY is just a valuable source of PLs and choline .…”

Section: Introductionmentioning

confidence: 99%

Biological Activities of Egg Yolk Lipids: A Review

Xiao

Zhao

Yao

et al. 2020

J. Agric. Food Chem.

110

View full text Add to dashboard Cite

As one of six dietary nutrients, lipid derived from different food matrices has been extensively studied and has an appropriate application in food, medicine, and cosmetic industry. Egg is a richly nutritive food, of which proteins and lipids possess excellent functional characteristics and biological activities. In recent years, egg yolk lipid has been successively separated and investigated, such as egg yolk oil, phospholipids, and fatty acids, which have anti-inflammatory activity, antioxidant activity, cardiovascular protection, and memory improvement, involving the regulation of cell function and physiological homeostatic balance. In this paper, the biological activities and underlying benefit of egg yolk lipids and fat-soluble components have been highlighted and summarized. Meanwhile, the quantitative data of egg yolk lipids needed to achieve any of the described biological effects and recommended concentrations relevant for dietary intake are reviewed. Finally, current challenges and crucial issues of high-efficiency utilization of egg yolk lipids are also discussed.

show abstract

“…Kovalcuks and Duma (2016) found that 97.89% PC and 99.81% PE were dissolved in ethanol. Chen et al (2019) optimized the extraction process of PC from egg yolk powder by ethanol, and the content of PC reached 75.59%. Luz and Wang (2005) extracted PC with ethanol and precipitated with acetone, and the purity of PC was more than 95%.…”

Section: Introductionmentioning

confidence: 99%

Enzymatic extraction and functional properties of phosphatidylcholine from chicken liver

Huang

et al. 2022

Poultry Science

View full text Add to dashboard Cite

Egg yolk phosphatidylcholine: Extraction, purification and its potential neuroprotective effect on PC12 cells

Cited by 22 publications

References 41 publications

Egg consumption and health effects: A narrative review

Egg consumption and health effects: A narrative review

Biological Activities of Egg Yolk Lipids: A Review

Enzymatic extraction and functional properties of phosphatidylcholine from chicken liver

Contact Info

Product

Resources

About