Ehlers-Danlos syndrome with huge bladder diverticulum in pregnancy – A rare and interesting case report

Pradhan, Neekita; Shilawant, Jyothi; Akkamahadevi, C.H.; Shivakumar, K.; Sundaresh, D.C.

doi:10.1016/j.ejogrb.2020.05.001

Cited by 4 publications

(4 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…They are linked to genetic disorders such as Ehlers-Danlos (type 9) syndrome, Menkes kinky hair syndrome, cutis laxa syndrome (Sotos), and Williams-Beuren syndrome. They require genetic testing to determine the etiology of the disease [2,4,8].…”

Section: Discussionmentioning

confidence: 99%

Multiple Bladder Diverticula Presenting in an 82-Year-Old Congolese Male

Manegabe

Nteranya

Balemba

et al. 2022

Case Reports in Surgery

View full text Add to dashboard Cite

Bladder diverticulum is a congenital malformation characterized by the outpouching of the bladder following an obstruction of urine flux. We present a case of 82-year-old Congolese male patient presented at our facility with a poor urinary stream and lower abdominal pain. A distended abdomen was found on physical examination while the external genitalia were normal. All blood laboratory values were found to be within normal ranges. The patient’s urine analysis revealed an uncountable number of white blood cells. Ultrasonography revealed multiple diverticula in the right posterolateral and posterior wall. An ultrasound of the abdomen revealed numerous bladder diverticula in the bladder’s left posterolateral and posterior aspects, mild right-sided hydronephrosis, and severe left hydronephrosis with a thinned-out cortex. Both ureters were normal. A computed tomographic (CT) scan of the abdomen confirmed the diagnosis. The patient underwent an open laparotomy which allowed complete ablation of the diverticula followed by bladder wall repair. A one-week course of antibiotics was prescribed, and the patient was discharged fully recovered with no immediate complications. Although bladder diverticula are a congenital malformation, the presence of multiple diverticula suggests that the condition is acquired. In elderly patients, open laparotomy combined with intravenous antibiotics yields positive results.

show abstract

Section: Discussionmentioning

confidence: 99%

Multiple Bladder Diverticula Presenting in an 82-Year-Old Congolese Male

Manegabe

Nteranya

Balemba

et al. 2022

Case Reports in Surgery

View full text Add to dashboard Cite

show abstract

“…Additionally, hyperemesis gravidarum, carpal tunnel syndrome and fatigue can be particularly challenging for those pregnant with hEDS/HSD (Pezaro, Pearce, Reinhold 2020). In one case study, bladder diverticulum (BD) has reportedly developed without any obstruction of the urinary bladder during pregnancy (Pradhan et al 2020). This may be because of the growing fetus pressing over the bladder where connective tissues may be compromised.…”

Section: Antenatal Care Considerationsmentioning

confidence: 99%

“…Consequently, in such instances, herniation and diverticulum can formulate and increase as the pregnancy progresses. Such cases may be managed conservatively unless chronic symptoms and complications arise in which case surgery may be required (Pradhan et al 2020).…”

Section: Antenatal Care Considerationsmentioning

confidence: 99%

“…As a baby born to a parent with hEDS/HSD has a 50% chance of inheriting it themselves (autosomal dominant pattern of inheritance), it has been suggested that these newborns be thoroughly examined for symptoms of these conditions at birth (Pradhan et al 2020). As with adults, supplementary joint support may also be required for babies affected during such examinations to avoid unnecessary trauma.…”

Section: Neonatal Care Considerationsmentioning

confidence: 99%

See 1 more Smart Citation

A clinical update on hypermobile Ehlers-Danlos syndrome during pregnancy, birth and beyond

Pezaro¹,

Pearce

Reinhold³

2021

British Journal of Midwifery

View full text Add to dashboard Cite

New estimates suggest that cases of hypermobile Ehlers-Danlos syndrome (hEDS) along with the related hypermobility spectrum disorders (HSD) affect approximately 1 in 20 pregnancies globally per year. As such, cases in maternity services should no longer be considered rare, only rarely diagnosed. These conditions can impact upon childbearing in different ways, yet healthcare professionals are often perceived to be lacking in awareness. This article updates and builds upon a previous international review of maternity care considerations for those childbearing with hEDS/HSD. Findings point to a need for individualised care planning in partnership with parents as part of a multidisciplinary approach. As our knowledge of these conditions has developed significantly in recent years, new research insights could usefully be embedded in staff and student education. As a first step, www.hEDSTogether.com has been launched hosting a freely downloadable EDS Maternity tool for use in practice, along with an i-learn module hosted by the Royal College of Midwives.

show abstract