2012
DOI: 10.1016/j.jip.2012.04.015
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Eicosanoid biosynthesis is activated via Toll, but not Imd signal pathway in response to fungal infection

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Cited by 28 publications
(28 citation statements)
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References 42 publications
(35 reference statements)
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“…Insect PGRPs can activate the Toll signal pathway inducing production of antibacterial peptides (AMPs) such as cecropin and gloverin [35], [36]. In our study, B. mori Toll receptor was induced the expression of 2.39-fold after DA treatment of 8 h (Table S1).…”
Section: Discussionmentioning
confidence: 63%
“…Insect PGRPs can activate the Toll signal pathway inducing production of antibacterial peptides (AMPs) such as cecropin and gloverin [35], [36]. In our study, B. mori Toll receptor was induced the expression of 2.39-fold after DA treatment of 8 h (Table S1).…”
Section: Discussionmentioning
confidence: 63%
“…In contrast, Ec infection induced a significant PLA 2 peak during the early 3 hr infection stage. This is the first report of an acute activation peak of PLA 2 in response to immune challenge, although there are several reports of the induction of PLA 2 activity in response to various pathogen infections (Park & Kim, ; Sadekuzzaman et al, ; Tunaz et al, ). The activation of PLA 2 activity may be induced via other immune mediators.…”
Section: Discussionmentioning
confidence: 74%
“…() studied the molecular cross‐talk between the Toll signalling pathway and prophenyloxidase activation and provided biochemical evidence that the Tenebrio Toll pathway, activation of prophenyloxidase, and melanin synthesis share a common serine protease for regulation of these innate immune responses. Park and Kim () showed that in Spodoptera exigua , biosynthesis of eicosanoids in the fat body and hemocytes was activated via the Toll signalling pathway in response to fungal challenge. Moreover, in the RNAi experiment, they showed that the nodule formation was significantly suppressed by dsRNA treatment specific to the Toll pathway in the S. exigua larvae during fungal infection.…”
Section: Discussionmentioning
confidence: 99%