Eight-Year Seroprevalence of HBV, HCV and HIV in Diyarbakir Training and Research Hospital

Abstract

Distribution of HBV, HCV and HIV results of the inpatients or outpatients, who had been treated for various diagnoses in Diyarbakır Training and Research Hospital between 2005 and 2012, among years was investigated.Files of the patients, who had been treated as inpatient or outpatient 992. to any diagnosis between 01/01/2005 and 31/12/2012 in the clinics or policlinics of Diyarbakır 581 due Training and Research Hospital, were retrospectively reviewed using patient file database. Serum samples (235.534 for HBsAg, 196.727 for Anti-HBs antibody, 98.497 for HBeAg, 97.417 for Anti-HBe antibody, 225.483 for HCV and 138.923 for HIV) of these patients, which had been processed in microbiology laboratory, were studied by chemiluminescence technique using Roche E-170 (Modular Analytics System) device.Prevalence rates between 2005 and 2012 were as follows: 15.9%-9% for HBsAg, 32.9%-52.3% for Anti-HBs, 2.5%-1.8% for HBeAg, 30.4%-25.2% for Anti-HBe, 1%-0.7% for Anti-HCV, and 0.1%-1% for Anti-HIV. Increase in Anti-HBs prevalence is the successful outcome of routine immunization in population. This suggests that, governmental policies focused on this subject have resulted in successful outcomes and that people also take care about this.A prevalence rate decreasing to 9% from 15.9% for HBsAg and prevalence rate increasing to 52.3% from 32.9% for Anti-HBs antibody positivity in 8-year period in our region is quite meaningful. Such favorable developments in our region are of great valuable in terms of indicating to what extent could struggle against HBV is controlled by education and awareness.

Evaluation of Risk Factors Associated with HBsAg and Anti-HCV Seropositivity: Results of a Nationwide Population Based Epidemiological Survey Study in Turkey

“…Our finding of 2.5% overall HBsAg positivity in our study population supports the claims that Turkey is an intermediate endemic region for HBV (2-7% HBsAg positivity) [6,7,13] . The prevalence of anti-HCV seropositivity (0.6%) was also similar to rates identified in previous studies conducted in Turkey [14,15] .…”

Üçüncü basamak bir hastaneye başvuran hastalarda HBsAg ve anti-HCV seroprevalansı: Altı yıllık retrospektif veriler

“…In this study, according to years, some regions have increased positivity and some regions have decreased. However, when studies are examined in general view, HBsAg seropositivity has declined over the years according to age groups in the world (12, [17][18][19]. In studies, the high positivity rate of patients who over 50 years of age is due to the more applies to hospital than other age groups.…”

“…Variability of HBsAg positivity might also change according to the barber, blood transfusion, dental treatment, etc. which have been diseases contagious factors (9,10,12,19,20).…”

“…About the age distribution of anti-HCV positivity, the highest positivity rate was found in patients over 49 years of age (1.4% in males and 1.7% in females) and lowest positivity rate in 0-14 and 14-25 age groups. When we look at the results of the studies conducted in the world, it is understood that anti-HCV positivity of 45 years old is higher than compared to other age groups (13)(14)(15)(19)(20)(21). In a study conducted in South Asia, it was reported that the positivity of patients who over 55 years old was more than 7% (13,19).…”

“…When we look at the results of the studies conducted in the world, it is understood that anti-HCV positivity of 45 years old is higher than compared to other age groups (13)(14)(15)(19)(20)(21). In a study conducted in South Asia, it was reported that the positivity of patients who over 55 years old was more than 7% (13,19). In some researches conducted in Turkey, over 50 age is recognized as an important risk factor for seropositivity (22).…”