Eighteen-year trajectories of depressive symptoms in mothers with a lifetime eating disorder: findings from the ALSPAC cohort

Chua, Yu Wei; Easter, Abigail; Lewis, Glyn; Solmi, Francesca

doi:10.1192/bjp.2019.89

Cited by 8 publications

(7 citation statements)

References 33 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Depressive symptomatology may follow a persistent trajectory over the lifetime, independently from eating disorder symptoms [83,84]. Approximately 50% of patients with AN report a minimum of one episode of a mood disorder during their lifetime [85,86].…”

Section: Chronic Stress Response: Co-morbidity With Depression and Anmentioning

confidence: 99%

Cognitive Interpersonal Model for Anorexia Nervosa Revisited: The Perpetuating Factors that Contribute to the Development of the Severe and Enduring Illness

Treasure

Willmott

Ambwani

et al. 2020

JCM

149

122

View full text Add to dashboard Cite

The cognitive interpersonal model was outlined initially in 2006 in a paper describing the valued and visible aspects of anorexia nervosa (Schmidt and Treasure, 2006). In 2013, we summarised many of the cognitive and emotional traits underpinning the model (Treasure and Schmidt, 2013). In this paper, we describe in more detail the perpetuating aspects of the model, which include the inter- and intrapersonal related consequences of isolation, depression, and chronic stress that accumulate in the severe and enduring stage of the illness. Since we developed the model, we have been using it to frame research and development at the Maudsley. We have developed and tested interventions for both patients and close others, refining the model through iterative cycles of model/intervention development in line with the Medical Research Council (MRC) framework for complex interventions. For example, we have defined the consequences of living with the illness on close others (including medical professionals) and characterised the intense emotional reactions and behaviours that follow. For the individual with an eating disorder, these counter-reactions can allow the eating disorder to become entrenched. In addition, the consequent chronic stress from starvation and social pain set in motion processes such as depression, neuroprogression, and neuroadaptation. Thus, anorexia nervosa develops a life of its own that is resistant to treatment. In this paper, we describe the underpinnings of the model and how this can be targeted into treatment.

show abstract

Section: Chronic Stress Response: Co-morbidity With Depression and Anmentioning

confidence: 99%

Cognitive Interpersonal Model for Anorexia Nervosa Revisited: The Perpetuating Factors that Contribute to the Development of the Severe and Enduring Illness

Treasure

Willmott

Ambwani

et al. 2020

JCM

149

122

View full text Add to dashboard Cite

show abstract

“…EPDS has been used for long-term follow-up of pregnant women and the assessment of longitudinal trajectories of depression [34]. In a population of British women, it showed relative stability between pregnancy and years eight to eleven postpartum and a slight increase between years eleven and eighteen [35]. EPDS has been used in high-, middle-, and low-income countries, including the Czech Republic [36][37][38][39][40][41].…”

Section: Implications Of All the Available Evidencementioning

confidence: 99%

Gender discrimination and depressive symptoms among child-bearing women: ELSPAC-CZ cohort study

et al. 2020

View full text Add to dashboard Cite

Background: Depression is approximately two-fold more prevalent among women than men. Social theories suggest that discrimination is a pathway through which gender inequalities affect women's lives, but data are lacking. This cohort study evaluates whether perceived gender discrimination is linked to depressive symptoms among child-bearing women. Methods: Data were obtained from 4,688 participants enrolled in pregnancy in 1991À92 in the European Longitudinal Cohort Study of Pregnancy and Childhood, Czech Republic. Perceived gender discrimination was assessed in mid-pregnancy, year seven, and year eleven. Depressive symptoms were assessed using the Edinburgh Postnatal Depression Scale at eight time-points between mid-pregnancy and year eleven postdelivery. Linear mixed error-component models of depressive symptoms were estimated. Findings: Perceived gender discrimination, reported by 10.7% of women, was related to higher depressive symptoms, both in the unadjusted analysis (b = 0.15 [95% confidence interval (CI): 0.12, 0.19], p < 0.001) and in the fully adjusted model (b = 0.12 [95% CI: 0.09, 0.16], p < 0.001). Covariates linked to higher depressive symptoms included financial hardship (b = 0.12 [95% CI: 0.10, 0.14], p < 0.001), childhood emotional/physical neglect (b = 0.18 [95% CI: 0.14, 0.22], p < 0.001), and childhood sexual abuse (b = 0.04 [95% CI: 0.03, 0.06], p < 0.001); an inverse relationship was evident for social support (À0.05 [95% CI: À0.07, À0.04], p < 0.001) and having a partner who performs female-stereotypical household tasks (b=À0.03 [95% CI: À0.05, À0.01], p = 0.001). Interpretation: The findings provide the first evidence that perceived gender discrimination is associated with depressive symptoms among child-bearing women. Social intervention programs aimed at reducing gender discrimination can potentially contribute to better mental health of women. Funding: Bill and Melinda Gates Foundation.

show abstract

“… ▶ ED-related attitudes and behaviours (Eating Disorder Scale, ED-15 [ 40 ]; six questions from the Avon Longitudinal Study of Parents and Children [ 41 ]). ▶ Motivation and readiness to change eating difficulties (two visual analogue scales; VAS).…”

Section: Methodsmentioning

confidence: 99%

“…▶ ED-related attitudes and behaviours (Eating Disorder Scale, ED-15 [ 40 ]; six questions from the Avon Longitudinal Study of Parents and Children [ 41 ]).…”

Section: Methodsmentioning

confidence: 99%

Characterising illness stages and recovery trajectories of eating disorders in young people via remote measurement technology (STORY): a multi-centre prospective cohort study protocol

Kuehne,

Phillips,

Moody

et al. 2024

BMC Psychiatry

View full text Add to dashboard Cite

Background Eating disorders (EDs) are serious, often chronic, conditions associated with pronounced morbidity, mortality, and dysfunction increasingly affecting young people worldwide. Illness progression, stages and recovery trajectories of EDs are still poorly characterised. The STORY study dynamically and longitudinally assesses young people with different EDs (restricting; bingeing/bulimic presentations) and illness durations (earlier; later stages) compared to healthy controls. Remote measurement technology (RMT) with active and passive sensing is used to advance understanding of the heterogeneity of earlier and more progressed clinical presentations and predictors of recovery or relapse. Methods STORY follows 720 young people aged 16–25 with EDs and 120 healthy controls for 12 months. Online self-report questionnaires regularly assess ED symptoms, psychiatric comorbidities, quality of life, and socioeconomic environment. Additional ongoing monitoring using multi-parametric RMT via smartphones and wearable smart rings (‘Ōura ring’) unobtrusively measures individuals’ daily behaviour and physiology (e.g., Bluetooth connections, sleep, autonomic arousal). A subgroup of participants completes additional in-person cognitive and neuroimaging assessments at study-baseline and after 12 months. Discussion By leveraging these large-scale longitudinal data from participants across ED diagnoses and illness durations, the STORY study seeks to elucidate potential biopsychosocial predictors of outcome, their interplay with developmental and socioemotional changes, and barriers and facilitators of recovery. STORY holds the promise of providing actionable findings that can be translated into clinical practice by informing the development of both early intervention and personalised treatment that is tailored to illness stage and individual circumstances, ultimately disrupting the long-term burden of EDs on individuals and their families.

show abstract

Eighteen-year trajectories of depressive symptoms in mothers with a lifetime eating disorder: findings from the ALSPAC cohort

Cited by 8 publications

References 33 publications

Cognitive Interpersonal Model for Anorexia Nervosa Revisited: The Perpetuating Factors that Contribute to the Development of the Severe and Enduring Illness

Cognitive Interpersonal Model for Anorexia Nervosa Revisited: The Perpetuating Factors that Contribute to the Development of the Severe and Enduring Illness

Gender discrimination and depressive symptoms among child-bearing women: ELSPAC-CZ cohort study

Characterising illness stages and recovery trajectories of eating disorders in young people via remote measurement technology (STORY): a multi-centre prospective cohort study protocol

Contact Info

Product

Resources

About