Ein neues gentechnologisches Modell zur Angiogeneseinduktion mittels ex vivo transfizierter isogener Fibroblasten

VEGF165 and bFGF protein-based therapy in a slow release system to improve angiogenesis in a bioartificial dermal substitute in vitro and in vivo

“…However, VEGF alone is known to induce instable vessel structures (leaky vessels) [17]. Previous in vivo studies have shown that VEGF 165 can induce temporary angiogenesis within several days [18].…”