The primary objective of this contribution is to show the intricate ways of over 100 years of research concerning the term Micoquian and its multiple shifts in meaning. A detailed analysis of the course of the research history has made it possible to identify several tendencies of shifting meaning. This concerned both its position within the chronology, its spatial extent, and decisive assemblage components. The term Micoquian has been used to describe complexes with very different characteristics. Chronologically, both assemblages dating before, during, and after the last interglacial period were referred to as Micoquian. To avoid difficulties in understanding the term, different names for the generic units of the respective assemblage units have been proposed from time to time. Due to the reflections on the research history, it is possible to investigate the question of whether and to what extent the term Micoquian should continue to be used and what significance is attached to it today, and to what extent it appears necessary to pursue other approaches to the classification of the Middle Paleolithic record. In conclusion, a multidisciplinary approach is proposed (including lithic, faunal, radiometric, site catchment, and/or settlement dynamic analysis) to build a multifaceted framework that is able to form clusters of similarities. The formerly defined generic units (called technocomplexes, facies, groups, space-time units, and so on) are seen purely as umbrella terms to structure the Paleolithic record, without claiming to reflect the former Paleolithic reality. With the addition of a tight chronological corset, the definitions of technocomplexes (by using lithic, faunal, and possibly floral data) could allow small, manageable space-time units to be formed and then compared with one another.