Einfluss unterschiedlicher Anr�hrfl�ssigkeiten auf die mechanischen und mikromorphologischen In-vitro-Eigenschaften von Hydroxylapatitzement

Nitsch, A.; A, Patyk; Schwartz, Pauline M.; Merten, H.–A.

doi:10.1007/s10006-005-0595-7

Cited by 4 publications

(2 citation statements)

References 13 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Calcibon ® and Norian SRS ® , on the other hand, have low porosity (0.93% and 0.48%, respectively), but display a relatively high compressive strength (33.9 MPa and 25.6 MPa, respectively). Our data are in line with previous measurements, which revealed a compression strength of 6.3-34 MPa for BoneSource ® [45,46], 35-55 MPa for Calcibon ® [34,47], 14-24 MPa for HydroSet™ [48], and 23-55 MPa for Norian SRS ® [49-51]. For MIIG ® X3, an in vivo compression strength of 0.6 MPa has been shown at 13 weeks follow up in a canine fracture model [52].…”

Section: Discussionsupporting

confidence: 93%

Microstructure and biomechanical characteristics of bone substitutes for trauma and orthopaedic surgery

Lieshout

Kralingen

El-Massoudi

et al. 2011

BMC Musculoskelet Disord

View full text Add to dashboard Cite

BackgroundMany (artificial) bone substitute materials are currently available for use in orthopaedic trauma surgery. Objective data on their biological and biomechanical characteristics, which determine their clinical application, is mostly lacking. The aim of this study was to investigate structural and in vitro mechanical properties of nine bone substitute cements registered for use in orthopaedic trauma surgery in the Netherlands.MethodsSeven calcium phosphate cements (BoneSource®, Calcibon®, ChronOS®, Eurobone®, HydroSet™, Norian SRS®, and Ostim®), one calcium sulphate cement (MIIG® X3), and one bioactive glass cement (Cortoss®) were tested. Structural characteristics were measured by micro-CT scanning. Compression strength and stiffness were determined following unconfined compression tests.ResultsEach bone substitute had unique characteristics. Mean total porosity ranged from 53% (Ostim®) to 0.5% (Norian SRS®). Mean pore size exceeded 100 μm only in Eurobone® and Cortoss® (162.2 ± 107.1 μm and 148.4 ± 70.6 μm, respectively). However, 230 μm pores were found in Calcibon®, Norian SRS®, HydroSet™, and MIIG® X3. Connectivity density ranged from 27/cm3 for HydroSet™ to 0.03/cm3 for Calcibon®. The ultimate compression strength was highest in Cortoss® (47.32 MPa) and lowest in Ostim® (0.24 MPa). Young's Modulus was highest in Calcibon® (790 MPa) and lowest in Ostim® (6 MPa).ConclusionsThe bone substitutes tested display a wide range in structural properties and compression strength, indicating that they will be suitable for different clinical indications. The data outlined here will help surgeons to select the most suitable products currently available for specific clinical indications.

show abstract

Section: Discussionsupporting

confidence: 93%

Microstructure and biomechanical characteristics of bone substitutes for trauma and orthopaedic surgery

Lieshout

Kralingen

El-Massoudi

et al. 2011

BMC Musculoskelet Disord

View full text Add to dashboard Cite

show abstract

“…The measured osteoid density serves for an evaluation of an early bone regeneration until 12 weeks postoperative. Zur Knochendefektfüllung im enossalen Lager werden neben nicht resorbierbaren Knochenersatzmaterialien (KEM) resorbierbare Knochenaufbaumaterialien (KAM) unterschiedlichen Ursprungs eingesetzt (14,24,26,27,30,33). Als Implantationsorte werden in tierexperimentellen Untersuchungen u. a. Tibiamarkraumund…”

Section: Discussionunclassified

Knochenregeneration unter Verwendung von Biopolymeren

Nitsch¹,

Verheggen²,

Ulmer³

et al. 2010

Osteologie

Self Cite

View full text Add to dashboard Cite

ZusammenfassungDas Ziel der Untersuchung war es, das Biopolymer Ethisorb® vergleichend mit dessen experimenteller Modifikation Ethisorb® Rapid sowie mit bzw. ohne Zusätze von autogenen Spongiosachips hinsichtlich der Osteoiddichte und damit die Frühphase der Knochenregeneration histomorphometrisch und -morphologisch zu untersuchen. Hierzu wurden die beiden Biopolymere in Defekte kritischer Größe des Tibiamarkraums an insgesamt 20 Göttinger Miniaturschweinen implantiert. Die postoperativen Standzeiten betrugen sechs, 12, 26 und 52 Wochen. Die vergleichsweise höchsten Osteoiddichten resultierten sechs bzw. zwölf Wochen postoperativ für Ethisorb® ,8 %) und Ethisorb® mit Spongiosachips (jeweils 0,9 %, p = 0,05). Zur Optimierung der Frühphase der Knochenregeneration bieten sich neben dem osteokonduktiv wirkenden Ethisorb® zusätzlich osteoinduktive autogene Spongiosachips an, die eine polytope Knochenregeneration mit appositionellen Osteoidbanden hervorrufen. Die ermittelte Osteoiddichte kann zur Beurteilung der frühen Knochenregeneration bis zwölf Wochen postoperativ herangezogen werden.

show abstract

Bone Substitute Materials in Trauma and Orthopedic Surgery – Properties and Use in Clinic

Lieshout¹

2012

Biomedical Materials and Diagnostic Devices

View full text Add to dashboard Cite

Einfluss unterschiedlicher Anr�hrfl�ssigkeiten auf die mechanischen und mikromorphologischen In-vitro-Eigenschaften von Hydroxylapatitzement

Abstract: To what extent the two mixing liquids of hydroxyapatite cement influence the resorption and bony substitution has to be shown in further studies.

Cited by 4 publications

References 13 publications

Microstructure and biomechanical characteristics of bone substitutes for trauma and orthopaedic surgery

Microstructure and biomechanical characteristics of bone substitutes for trauma and orthopaedic surgery

Knochenregeneration unter Verwendung von Biopolymeren

Bone Substitute Materials in Trauma and Orthopedic Surgery – Properties and Use in Clinic

Contact Info

Product

Resources

About