Einhaltung von Therapieempfehlungen - Eine prospektive Studie mit zwei Verabreichungsmodi für Trinknahrungen

Baumann, Andreas; Dolder, Andrea; Stanga, Zeno; Joray, Maya Lucia; Kurmann, Silvia

doi:10.1055/s-0033-1343674

Cited by 4 publications

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“…Body weight was increased in MEDPass versus conventional ONS administration in one previous RCT [24]. Other non-RCTs found no difference in body weight between groups [13,14]. HGS was only evaluated in one small non-RCT (n ¼ 10) and found a trend to higher HGS with MEDPass administration [13].…”

Section: Secondary Outcomesmentioning

confidence: 96%

“…Other non-RCTs found no difference in body weight between groups [13,14]. HGS was only evaluated in one small non-RCT (n ¼ 10) and found a trend to higher HGS with MEDPass administration [13]. Together with the results of the MEDPass Trial, it remains unclear if MEDPass administration improves the course weight or HGS.…”

Section: Secondary Outcomesmentioning

confidence: 99%

“…waste in the MEDPass group was two liters versus 30.8 L with conventional administration (p < 0.001)[25]. Baumann et al calculated theoretical cost efficiency which was better with the MEDPass mode of administration[13].4.3.3. Patient preferencesCampell et al surveyed 25 patients each on MEDPass and conventional administration in their non-randomized trial with the European Quality of Life 5 Dimensions questionnaire and found higher overall QOL in patients on MEDPass admininistration (p ¼ 0.004)…”

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confidence: 99%

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MEDPass versus conventional administration of oral nutritional supplements – A randomized controlled trial comparing coverage of energy and protein requirements

Kurmann¹,

Reber²,

Schönenberger³

et al. 2023

Clinical Nutrition

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Section: Secondary Outcomesmentioning

confidence: 96%

Section: Secondary Outcomesmentioning

confidence: 99%

mentioning

confidence: 99%

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MEDPass versus conventional administration of oral nutritional supplements – A randomized controlled trial comparing coverage of energy and protein requirements

Kurmann¹,

Reber²,

Schönenberger³

et al. 2023

Clinical Nutrition

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“…The MEDPass administration mode offers a different approach, in which ONS are distributed on medication rounds three or four times per day in unusually small portions (50–120 ml) [ 16 – 22 ]. Preliminary trials suggest that the MEDPass administration mode improves compliance and cost effectiveness [ 17 , 19 , 22 , 23 ].…”

Section: Introductionmentioning

confidence: 99%

Energy and protein intake in medical and geriatric inpatients with MEDPass versus conventional administration of oral nutritional supplements: study protocol for the randomized controlled MEDPass Trial

Kurmann

Reber

Vasiloglou

et al. 2021

Trials

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Background Disease-related malnutrition is highly prevalent in hospitalized medical and geriatric inpatients. It is associated with negative outcomes such as muscle wasting, decline of functional status, and increased morbidity and mortality. Oral nutritional supplements (ONS) are frequently used in nutritional therapy to increase intake. However, compliance to ONS is often limited and maybe improved by prescribing ONS in small portions timed with the medication (MEDPass). However, it is unknown whether the MEDPass administration enhances patients’ total energy and protein intake. Methods The MEDPass Trial is a randomized, controlled, open-label superiority trial. Patients in the MEDPass group receive 50 ml of ONS four times per day, distributed with the medication rounds. Patients in the control group receive ONS between meals. The primary outcome is average daily energy intake (% of calculated daily requirement). For our power analysis, we assumed that administration of ONS in the MEDPass administration mode increases energy intake by at least 10% (i.e., by 200 kcal for an average energy requirement of 2200 kcal/day). Thus, with the inclusion of 200 patients, this trial has 80% power to demonstrate that intervention group patients have an average intake of 2200 kcal/day (SD 500 kcal) versus 2000 kcal/day (SD 500 kcal) in control group patients. Energy and protein intakes from ONS and all food consumed are monitored continuously throughout the hospital stay and are statistically compared to the patient’s requirements. Secondary outcomes include average daily protein intake (% of calculated daily requirement), average intake of ONS/day, the course of body weight, handgrip strength, appetite, and nausea. Furthermore, hospital length of stay and 30-day mortality are assessed. The primary statistical analysis will be performed as an intention-to-treat analysis adjusted for the stratification factors used in randomization. Discussion To our knowledge, this is the first randomized controlled trial assessing total energy and protein intake for the entire hospitalization period in patients receiving MEDPass versus conventional ONS administration. Thus, the MEDPass Trial will fill a gap and answer this relevant clinical question. Trial registration ClinicalTrials.gov NCT03761680. Registered on 3 December 2018. Kofam.ch SNCTP000003191. Registered on 15 October 2018

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Ernährung

Imoberdorf,

Ballmer,

Rühlin

2024

Onkologische Krankenpflege

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Einhaltung von Therapieempfehlungen - Eine prospektive Studie mit zwei Verabreichungsmodi für Trinknahrungen

Cited by 4 publications

References 0 publications

MEDPass versus conventional administration of oral nutritional supplements – A randomized controlled trial comparing coverage of energy and protein requirements

MEDPass versus conventional administration of oral nutritional supplements – A randomized controlled trial comparing coverage of energy and protein requirements

Energy and protein intake in medical and geriatric inpatients with MEDPass versus conventional administration of oral nutritional supplements: study protocol for the randomized controlled MEDPass Trial

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