In the standard Bell scenario, when making a local projective measurement on each system component, the amount of randomness generated is restricted. However, this limitation can be surpassed through the implementation of sequential measurements. Nonetheless, a rigorous definition of random numbers in the context of sequential measurements is yet to be established, except for the lower quantification in device-independent scenarios. In this paper, we provide the definition of quantum intrinsic randomness in sequential measurements and quantify the randomness in the Collins-Gisin-Linden-Massar-Popescu (CGLMP) inequality sequential scenario. Initially, we investigate the quantum intrinsic randomness of the mixed states under sequential projective measurements and the intrinsic randomness of the sequential non-projective measurements under pure states. Naturally, we rigorously define quantum intrinsic randomness under sequential non-projective measurement for arbitrary quantum states. Furthermore, we apply our method to one-Alice and two-Bobs sequential measurement scenarios and quantify the quantum intrinsic randomness of the maximally entangled state and maximally violated state by giving an extremal decomposition. Finally, using the sequential NPA hierarchy in the device-independent scenario, we derive lower bounds on the quantum intrinsic randomness of the maximally entangled state and maximally violated state.