Ektopes Schilddrüsengewebe in der Nebenniere

Rawitzer, Josefine; Kapakoglou, A.; Walz, Martin K.; Schmid, Kurt Werner; Reis, Henning

doi:10.1007/s00292-019-00724-4

Cited by 11 publications

(6 citation statements)

References 12 publications

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“…Most of adrenal lesions were incidentally discovered by CT or MRI, some of those (three out of thirteen) were discovered during preoperative diagnostic of other organ pathology. Some patients had discomfort or pain in the back (15,17,19). In three patients preoperatively hyperaldosteronism was detected (13,14,15).…”

Section: Discussionmentioning

confidence: 97%

“…Along this route thyroid tissue may fail to migrate properly, and that's how ectopic thyroid can occur. Also ectopic thyroid tissue can be found in subdiaphragmatic organs, such as the gallbladder, ovary, pancreas, duodenum, vagina and the adrenal glands (2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19). Besides this theory of migration, the most uncommon thing is that adrenal is composed of medulla which is ectodermic in origin, and cortex which arise from mesoderm.…”

Section: Discussionmentioning

confidence: 99%

“…It is difficult to understand how ectopic thyroid tissue may occur in the thoracic cavity, duodenum, gallbladder, pancreas, ovaries and adrenals (2)(3)(4)(5)(6)(7). Extremely rare cases of ectopic thyroid tissue in the adrenal were described before in 14 patients to the best of our knowledge (8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19). The frequency of incidental adrenal tumors on computed tomography (CT) scans is approximately 0.4-4.4%, and in autopsy series incidence of 8.7% has been reported (20).…”

Section: Introductionmentioning

confidence: 99%

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Ectopic thyroid tissue in adrenal gland, case report and review of literature

Paunović¹,

Rovčanin

Jovanovic

et al. 2020

Gland Surg

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Ectopic thyroid tissue is a rare pathological finding bellow the diaphragm and extremely rare finding is ectopic thyroid tissue in the adrenal gland (ETTAG). Thyroid tissue can be located anywhere along the way of embryological migration pathway of thyroglossal duct. In most cases of ectopic thyroid tissue, it is located in the neck. Here we present a case of 29 years old patient that was laparoscopically operated because of adrenal incidentaloma which showed 28 mm in maximal diameter on MRI. The patient had normal adrenal function. Pathohistological finding confirmed ETTAG. Follicular cells express TTF-1, Thyroglobulin, PAX8, and cytokeratin 7, and lack expression of calretinin. This is the 15th such case described in literature. Women are much more affected than men (14:1), and it usually presents in the fifth decade (mean age 49). In all cases ETTAG was composed of normal follicular cells, and C cells were not found. Review of the literature reveals that adrenal ectopic thyroid tissue is almost always cystic, and has distinctive pathologic features. The most important thing is that ETTAG must be distinguished from metastatic deposits from thyroid gland carcinoma.Our patient had normal thyroid function, without any nodules in thyroid gland. We report the youngest patient with ectopic thyroid tissue located in the adrenal gland.

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Section: Discussionmentioning

confidence: 97%

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Ectopic thyroid tissue in adrenal gland, case report and review of literature

Paunović¹,

Rovčanin

Jovanovic

et al. 2020

Gland Surg

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“…Kod 12 pacijenata se radilo o incidentalno otkrivenom uvećanom nadbubregu a kod 3 pacijenta ova promena je otkrivena u toku pripreme za operaciju tumora druge lokalizacije u abdomenu. Anamnestički bol i neprijatnost u leđima osećalo je 3 pacijenta (15,17,19). Kod 3 pacijenta bio je prisutan konkomitantni hiperaldosteronizam (13)(14)(15).…”

Section: Slika 1 Mri Na Kome Se Prezentuje Ektopično Tkivo šTitaste unclassified

“…Obzirom na dobro poznavanje embriogeneze i putanju nastanka štitaste žlezde jako je teško objasniti kako i zašto se ektopično tkivo štitaste žlezde može naći u toraksu, duodenumu, žučnoj kesi, pankreasu, ovarijumima ili u nadbubregu (2-7). Pravi raritet predstavlja ektopično tkivo štitaste žlezde u nadbubrežnoj žlezdi i do sada je objavljeno 15 ovakvih slučajeva (8)(9)(10)(11)(12)(13)(14)(15)(16)(17)(18)(19).…”

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Incidence of ectopic thyroid tissue in the adrenal gland

Buzejic¹,

Odalovic²,

Zoric³

et al. 2019

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Ectopic thyroid tissue is a rare pathological finding bellow the diaphragm and extremely rare finding is ectopic thyroid tissue in the adrenal gland. Thyroid tissue can be located anywhere along the way of embryological migration pathway of thyroglossal duct. In most cases of ectopic thyroid tissue, it is located in the neck. Pathohistologically ectopic thyroid tissue in all cases was formed of follicular cells that expressed TTF-1, Thyroglobulin, PAX8, and cytokeratin 7, and there was lack expression of calretinin. In the literature we found 15 such cases. Women are much more affected than men (14:1), and it usually presents in the fifth decade (mean age 49). In all cases it was composed of normal follicular cells, and C cells were not found. Review of the literature reveals that adrenal ectopic thyroid tissue is almost always cystic, and has distinctive pathologic features. The most important thing is that ectopic thyroid tissue must be distinguished from metastatic deposits from thyroid gland carcinoma.

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Ectopic thyroid tissue in adrenal gland – A case report and review of literature

Vijayakumar,

Mahender,

Bose

et al. 2024

Diagn Pathol

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Ectopic thyroid tissue along the line of descent of thyroid from foramen caecum along thyroglossal duct to the normal anatomic location in neck has been reported. Ectopic thyroid tissue in adrenal gland (ETTAG) is rarely encountered and very few cases have been reported in literature. The most common differential diagnosis to be considered when thyroid follicles are noted in adrenal gland are metastasis from a thyroid malignancy or a teratoma or an ectopic thyroid tissue in adrenal gland. We present a case of an adrenal incidentaloma in a young pregnant female which was diagnosed to be ectopic thyroid tissue in adrenal gland. The review of literature of similar cases of this rare embryological aberrance is discussed. To our knowledge, only 16 such cases have been documented in literature and our case is the first one from Indian subcontinent and the largest documented with respect to size.

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Ektopes Schilddrüsengewebe in der Nebenniere

Cited by 11 publications

References 12 publications

Ectopic thyroid tissue in adrenal gland, case report and review of literature

Ectopic thyroid tissue in adrenal gland, case report and review of literature

Incidence of ectopic thyroid tissue in the adrenal gland

Ectopic thyroid tissue in adrenal gland – A case report and review of literature

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