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Dorko, Erik; Kmeťová, M; Marossy, A; Dorko, F; Molokacova, M.

doi:10.1023/a:1007178806720

Cited by 20 publications

(2 citation statements)

References 32 publications

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“…The latter was first isolated from kefir in 1909 and reported under the obsolete name Saccharomyces fragilis (3). The ecology of this yeast is not fully understood, although it appears to thrive in diverse habitats, including dairy products (4)(5)(6)(7)(8)(9)(10).…”

Section: Andida Kefyr (Formerly Candida Pseudotropicalis) Is a Yeasmentioning

confidence: 99%

Epidemiology of Candida kefyr in Patients with Hematologic Malignancies

et al. 2014

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g Candida kefyr is an emerging pathogen among patients with hematologic malignancies (HM). We performed a retrospective study at Johns Hopkins Hospital to evaluate the epidemiology of C. kefyr colonization and infection in HM patients between 2004 and 2010. Eighty-three patients were colonized and/or infected with C. kefyr, with 8 (9.6%) having invasive candidiasis (IC). The yearly incidence of C. kefyr colonization and candidemia increased over the study period (P < 0.01), particularly after 2009. In 2010, C. kefyr caused 16.7% of candidemia episodes. The monthly incidence of C. kefyr was higher during the summer throughout the study. In a cohort of patients with acute myelogenic leukemia receiving induction chemotherapy, risks for C. kefyr colonization included the summer season (odds ratio [OR], 3.1; P ‫؍‬ 0.03); administration of an azole (OR, 0.06; P < 0.001) or amphotericin B (OR, 0.35; P ‫؍‬ 0.05) was protective. Fingerprinting of 16 isolates by repetitive sequence-based PCR showed that all were different genotypes. The epidemiology of C. kefyr candidemia was evaluated in another hospital in Montreal, Canada; data confirmed higher rates of C. kefyr infection in the summer. C. kefyr appears to be increasing in HM patients, with prominent summer seasonality. These findings raise questions about the effect of antifungal agents and health care exposures (e.g., yogurt) on the epidemiology of this yeast.

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Section: Andida Kefyr (Formerly Candida Pseudotropicalis) Is a Yeasmentioning

confidence: 99%

Epidemiology of Candida kefyr in Patients with Hematologic Malignancies

et al. 2014

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“…Like other Candida species, C. lusitaniae can also adhere to plastic surfaces, such as indwelling catheters, cannulas, and drains. 65 The ALS gene family members, EAP1, ECM33, HWP1, IFF4, INT1 , and MP65 , are encoding for the major C. albicans adhesins. 66 Even though none of the putative orthologs of these genes have been characterized in C. lusitaniae , these can be found within its genome ( Table 1 ), making it likely that adhesion occurs via these cell surface adhesins.…”

Section: The Virulence Factors Repertoirementioning

confidence: 99%

Candida lusitaniae: Biology, Pathogenicity, Virulence Factors, Diagnosis, and Treatment

Mendoza-Reyes¹,

Gómez-Gaviria²,

Mora-Montes³

2022

IDR

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The incidence of fungal infections is increasing at an alarming rate and has posed a great challenge for science in recent years. The rise in these infections has been related to the increase in immunocompromised patients and the resistance of different species to antifungal drugs. Infections caused by the different Candida species, especially Candida albicans , are one of the most common mycoses in humans, and the etiological agents are considered opportunistic pathogens associated with high mortality rates when disseminated infections occur. Candida lusitaniae is considered an emerging opportunistic pathogen that most frequently affects immunocompromised patients with some comorbidity. Although it is a low-frequency pathogen, and the mortality rate of C. lusitaniae -caused candidemia does not exceed 5%, some isolates are known to be resistant to antifungals such as amphotericin B, 5-fluorocytosine, and fluconazole. In this paper, a detailed review of the current literature on this organism and its different aspects, such as its biology, possible virulence factors, pathogen-host interaction, diagnosis, and treatment of infection, is provided. Of particular interest, through Blastp analysis we predicted possible virulence factors in this species.

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Current Awareness

2001

Yeast

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In order to keep subscribers up‐to‐date with the latest developments in their field, this current awareness service is provided by John Wiley & Sons and contains newly‐published material on yeasts. Each bibliography is divided into 10 sections. 1 Books, Reviews & Symposia; 2 General; 3 Biochemistry; 4 Biotechnology; 5 Cell Biology; 6 Gene Expression; 7 Genetics; 8 Physiology; 9 Medical Mycology; 10 Recombinant DNA Technology. Within each section, articles are listed in alphabetical order with respect to author. If, in the preceding period, no publications are located relevant to any one of these headings, that section will be omitted. (4 weeks journals ‐ search completed 3rd Jan. 2001)

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Cited by 20 publications

References 32 publications

Epidemiology of Candida kefyr in Patients with Hematologic Malignancies

Epidemiology of Candida kefyr in Patients with Hematologic Malignancies

Candida lusitaniae: Biology, Pathogenicity, Virulence Factors, Diagnosis, and Treatment

Current Awareness

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