Elastic kirigami patch for electromyographic analysis of the palm muscle during baseball pitching

Yamagishi, Kazumasa; Nakanishi, Takenori; Mihara, Sho; Azuma, Masaru; Takeoka, Shinji; Kanosue, Kazuyuki; Nagami, Tomoyuki; Fujie, Toshinori

doi:10.1038/s41427-019-0183-1

Cited by 30 publications

(24 citation statements)

References 37 publications

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“…The signal was obtained by having the subject grab and release a baseball every 3 s, which was repeated 5 times. The SNR was calculated using the following equation [31][32][33]…”

Section: Methodsmentioning

confidence: 99%

Polymer Nanosheet Interfaced Bioelectrode for Skin‐Inert sEMG Measurement

Ito

Horii

Fujie

2021

Adv Materials Inter

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poly(ethylene glycol), poly(methacrylic acid), and polyacrylamide. [2] The strong adhesive of the electrode is required for good contact with the body surface, which is crucial to ensure signal transduction and high-quality performance. However, for acute measurements, especially for infants and people with sensitive skin, [3] the adhesiveness of the pre-gel electrode and direct contact between the pre-gel electrode and skin may cause discomfort and skin irritation at measurement sites. [4] In this regard, the hypoallergenic hydrogel electrode which has a different adhesive gel content was invented to overcome this problem. Nonetheless, the dry electrode fabricated on a rigid substrate was not sufficiency flexible to conform to human skin, leading to insufficient electrical performance.A free-standing polymeric ultrathin film (or nanosheet) is attractive to use for skin-contact application owing to its high adhesiveness and ultra-flexibility that allow the nanosheet to conform on various surfaces including skin [5] and internal organs [6][7][8] without additional glue or adhesive. The recent development of nanosheet technology involving fabrication with drugs, [5,8] fluorescent dyes, [9] conductive polymers, [10][11][12] and cells [13][14][15][16] has been applied to a variety of biomedical applications from surgical intervention to tissue engineering and health-care devices. [17] In our previous report, a conductive polymer nanosheet was fabricated for use in ultraconformable electrodes for bioelectrical signal monitoring. [10] However, with the conductive nanosheet itself, measurement limitations were observed for some flexible parts of the body such as wrists due to the instability of the mechanical robustness resulting from body motion and the electrode placement area, leading to poor measurement efficiency.To avoid such mechanical mismatch, in this study, elastomers were selected to fabricate the nanosheets because of their unique properties; they are elastic, flexible, or tough depending on the polymer morphology. One of the particularly attractive properties of elastomers is the glass transition temperature (T g ) at which the polymeric chains of the elastomer change from a glassy state to a rubbery state. In particular, elastomers have a brittle and rigid-like structure below T g and a loose and flexible structure above T g , which exhibit reversible properties under external force. On the basis of their mechanical properties, polystyrene-polybutadiene-polystyrene triblock copolymer (SBS)The interface between skin and electrodes plays a major role in the accuracy and efficiency of biopotential measurements. For reliable biosignal recording, stable and low-impedance contact is required between electrodes and the target tissue. Conventional wet electrodes (Ag/AgCl) are composed of metal electrodes with skin-adhesive hydrogel. However, for long-term measurement, direct contact between the pre-gel electrode and skin causes discomfort and skin irritation, especially for infants and people with sensitive skin b...

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“…The signal was obtained by having the subject grab and release a baseball every 3 s, which was repeated 5 times. The SNR was calculated using the following equation [31][32][33]…”

Section: Methodsmentioning

confidence: 99%

Polymer Nanosheet Interfaced Bioelectrode for Skin‐Inert sEMG Measurement

Ito

Horii

Fujie

2021

Adv Materials Inter

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“…Moreover, by utilizing the slow biodegradation characteristics of PDLLA, we will also envision unique devices that will naturally degrade after a certain period of use. Also, the polymeric thin film has the potential as a platform of biomonitoring device, [44,45] which may enable the development of thin-film devices that combine therapeutic and monitoring functions.…”

Section: Evaluation Of the In Vivo Heat Generationmentioning

confidence: 99%

Flexible Induction Heater Based on the Polymeric Thin Film for Local Thermotherapy

Saito

Kanai

Fujita

et al. 2021

Adv Funct Materials

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Local delivery of physical energy, such as heat, is promising for the treatment of target lesions without the unintended distribution of heat to other normal tissue. However, the heating device must be equipped with an external power source or strong magnetic field to operate the device, and many of them are too large to be placed inside the body. In this regard, wireless, lightweight, flexible electronics can be used for the miniaturization of implantable devices. In this study, a flexible induction heating (IH) device is reported that integrates inkjet‐printed wirings and flexible polymeric thin films, specifically Au nanoink‐based wirings (thickness: 1.5 µm) and a biodegradable poly(D, L‐lactic acid) (PDLLA) thin film (thickness: 5 µm). A unique method of transferring the inkjet‐printed Au nanoink wiring onto the PDLLA thin film realizes the integration of the following technical features in one device: biocompatible packaging, a printed IH system, and body conformability. The resulting thin‐film IH device is successfully placed on a hepatic lobe of a beagle dog, which allows for a local increase in temperature of 7 °C after 1‐min power feeding without tissue inflammation. The thin‐film IH device is expected to provide minimally invasive thermotherapy when combined with endoscopic surgery.

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“…We have reported the treatment of visceral pleural defects using polysaccharide nanosheets, which reduced tissue adhesions compared with the results obtained with conventional fibrin glues 13 . We used nanosheets as electrodes by coating them with conductive polymers, and we reported the application of such nanosheet electrodes for biomonitoring during sport and in daily life 14 …”

Section: Introductionmentioning

confidence: 99%

Preparation and characterization of highly elongated polydimethylsiloxane nanosheets

Mihara

Takeoka

2022

Polymers for Advanced Techs

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Polydimethylsiloxane (PDMS) is a biocompatible polymer that exhibits high flexibility and heat resistance. PDMS can be rapidly cross‐linked at low temperatures by a platinum‐catalyzed addition reaction and is used to create nanostructures owing to its high formability. In this study, free‐standing PDMS thin films (PDMS nanosheets) were fabricated and characterized. PDMS nanosheets, about 90–2500 nm thick, were prepared using a microgravure coater. The mechanical properties of the PDMS nanosheets depended on the amount of cross‐linker added in preparation. For example, a 93‐nm‐thick PDMS nanosheet showed high flexibility with elongation at break of 338% and Young's modulus of 0.46 MPa. The adhesion strength of the PDMS nanosheets was also dependent on the amount of cross‐linker, and the lesser the cross‐linker, the higher the adhesion strength. The PDMS nanosheets showed no change in physical properties when annealed at 150°C. Flexible, adhesive, and heat‐resistant PDMS nanosheets were demonstrated as a substrate for skin‐contact strain sensors and showed resistance changes of 20%–30% in response to skin stretching.

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Elastic kirigami patch for electromyographic analysis of the palm muscle during baseball pitching

Cited by 30 publications

References 37 publications

Polymer Nanosheet Interfaced Bioelectrode for Skin‐Inert sEMG Measurement

Polymer Nanosheet Interfaced Bioelectrode for Skin‐Inert sEMG Measurement

Flexible Induction Heater Based on the Polymeric Thin Film for Local Thermotherapy

Preparation and characterization of highly elongated polydimethylsiloxane nanosheets

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