An understanding of biotissue-bubble interactions and the stresses induced in the tissue is needed to identify potential mechanisms of tissue damage, such as vessel rupture, by acoustically excited bubbles. Interactions between acoustically excited bubbles and nearby rigid structures have been studied effectively using the boundary element method. However, if the nearby structure is a biotissue, structure deformations will affect the bubble response. In this paper a coupled finite element and boundary element code, developed to investigate the interactions between an acoustically excited bubble and a deformable structure, is presented. In particular, this model was developed to investigate the response of bubbles within deformable tubes. This code is validated by comparison to other simulation and experimental results and employed to obtain the response of an acoustically excited bubble centered within a tube. General characteristics of bubble-tube interactions and stresses induced in the tube wall are described by considering typical simulation results.