In this work, a face-based smoothed point interpolation method (FS-PIM) is formulated for three-dimensional (3D) thermal elastic-plastic analysis of structures. For this method, field functions are approximated using second order PIM shape functions and the face-based smoothing domains are used to perform the numerical integration. The material properties are considered to be temperature-dependent and the plastic behavior is studied through the Von Mises yield function. Numerical examples with different kinds of boundary conditions are investigated to verify the validity of the present method. The obtained results indicate that FS-PIM is an effective technique for the thermal elastic-plastic analysis of structures.