Herrn H. Nowack zum 65. Geburtstag gewidmet Very often, different approaches are used for crack initiation and crack growth predictions. The current article introduces a recently developed approach that can be used for the predictions of both crack initiation and crack propagation. A basic assumption is that both crack nucleation and crack growth are governed by the same fatigue damage mechanisms and a single fatigue damage criterion can model both stages. A rule is that any material point fails to form a fresh crack if the total accumulated fatigue damage reaches a limit. For crack initiation predictions, the stresses and strains are obtained either directly from experiments or though a numerical analysis. For the prediction of crack growth, the approach consists of two steps. Elastic-plastic stress analysis is conducted to obtain the detailed stress-strain responses. A general fatigue criterion is used to predict fatigue crack growth. Compact specimens made of 1070 steel were experimentally tested under constant amplitude loading with different R-ratios and the overloading influence. The capability of the approach to predict both crack initiation and the crack growth under these loading conditions was demonstrated by comparing the predictions with the experimental observations.Keywords: Crack growth, crack initiation, continuum mechanics, fatigue prediction.