2020
DOI: 10.1088/1361-6560/abca00
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Elastography imaging: the 30 year perspective

Abstract: From the development of x-ray imaging in the late 19th century, the field of medical imaging developed an impressive array of modalities. These can measure and image a variety of physical parameters from absorption coefficients to spin–spin relaxations. However, throughout most of the 20th century, the intrinsic biomechanical properties of tissues remained hidden from conventional radiology. This changed around 1990 when it was demonstrated that medical ultrasound systems with their fast pulse repetition rate … Show more

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Cited by 52 publications
(41 citation statements)
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“…Assuming that pressure alterations in highly vascularized organs such as the liver and the spleen affect the whole organ ( Parker, 2014 ; Parker, 2015 ), we believe that measurement of the stiffness response to pressure should cover the entire organ. However, only a few ultrasound-based elastography techniques can generate stiffness maps of large areas of the liver or the spleen ( Ormachea and Parker, 2020 ). These methods exploit time-harmonic wave stimulation to induce superimposed wave fields from different directions in the abdomen and are therefore referred to as time-harmonic elastography (THE) ( Tzschätzsch et al, 2014 ) or reverberant elastography ( Parker et al, 2017 ).…”
Section: Introductionmentioning
confidence: 99%
“…Assuming that pressure alterations in highly vascularized organs such as the liver and the spleen affect the whole organ ( Parker, 2014 ; Parker, 2015 ), we believe that measurement of the stiffness response to pressure should cover the entire organ. However, only a few ultrasound-based elastography techniques can generate stiffness maps of large areas of the liver or the spleen ( Ormachea and Parker, 2020 ). These methods exploit time-harmonic wave stimulation to induce superimposed wave fields from different directions in the abdomen and are therefore referred to as time-harmonic elastography (THE) ( Tzschätzsch et al, 2014 ) or reverberant elastography ( Parker et al, 2017 ).…”
Section: Introductionmentioning
confidence: 99%
“…In recent years, various elastography techniques for evaluating and imaging tissue elasticity quantitatively and objectively in diagnostic imaging have been put into practical use, and the amount of clinical knowledge has increased [1][2][3]. In addition, some diagnostic guidelines have been issued [4], many review papers on technology and clinical applications have been published [5][6][7][8][9][10], and the status as a diagnostic technology is in the process of being established.…”
Section: Introductionmentioning
confidence: 99%
“…On the other hand, there are methods to measure how strain is distributed through tissues in response to an applied force. Elastography is the quantitative imaging of strain distribution in soft tissue and was initially developed using the transducer of a B-scan ultrasound to compress the tissues externally [ 29 , 30 ]. Ultrasound elastography was developed to measure the stiffness of breast and prostate cancer lesions but has since been used in a variety of other clinical applications [ 31 , 32 ].…”
Section: Tissue Stress Strain and Stiffness Measurement In Vivomentioning
confidence: 99%