Elastosis perforans serpiginosa: a review of the literature and report of 11 cases

Mehregan, Amir H.

doi:10.1001/archderm.97.4.381

Cited by 121 publications

(66 citation statements)

References 34 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…26 The association with DS has been recognized as early as 1955. 4 While some studies have found it to be more common in DS, 27,28 others suggest no association. 9 Reactive perforating collagenosis (RPC), another perforating disorder, has also been reported in DS.…”

Section: Elastosis Perforans Serpiginosa (Eps)mentioning

confidence: 99%

Dermatological Manifestations of Down's Syndrome

Barankin

Guenther

2001

Journal of Cutaneous Medicine and Surgery: Incorporating Medica

View full text Add to dashboard Cite

Background: Down's syndrome (DS) is an extensively researched congenital condition characterized by mental retardation and distinct physical features. The cutaneous manifestations of DS are numerous, yet they seldom receive appropriate attention.Objective: To review the dermatological conditions associated with DS.Methods: A review of the medical literature.Results: DS is associated with an increased incidence of numerous dermatological conditions, some of which may be related to an immunological deficiency.Conclusion: Along with the importance of understanding the physical and psychosocial aspects of DS, an appreciation of the dermatological manifestations of this condition is integral to comprehensive medical care.

show abstract

Section: Elastosis Perforans Serpiginosa (Eps)mentioning

confidence: 99%

Dermatological Manifestations of Down's Syndrome

Barankin

Guenther

2001

Journal of Cutaneous Medicine and Surgery: Incorporating Medica

View full text Add to dashboard Cite

show abstract

“…As was present in this case, a variable degree of granulomatous inflammation is often observed in the dermis 11,12 . Transepidermal elimination of abnormally large and tortuous eosinophilic 'bramble-bush' elastic fibers is an additional feature of penicillamine-induced EPS 13 .…”

Section: Discussionmentioning

confidence: 99%

Penicillamine-induced Elastosis Perforans Serpiginosa and Cutis Laxa in a Patient with Wilson's Disease

Choi

Kim

et al. 2010

Ann Dermatol

View full text Add to dashboard Cite

Elastosis perforans serpiginosa (EPS) is a rare reactive perforating dermatosis that is characterized by the transepidermal elimination of abnormal elastic fibers. Penicillamine, which is one of the clear triggers for EPS, is a heavy metal chelator that is primarily used for disorders such as cystinuria and Wilson's disease. It may cause alterations in the dermal elastic tissue such as pseudo-pseudoxanthoma elasticum, acquired cutis laxa, EPS and anetoderma. Herein we present a case of cutis laxa and EPS in a 34-year-old man who was previously on a long-term, high-dose of penicillamine for Wilson's disease. The combination of EPS and cutis laxa induced by penicillamine has rarely been reported and we report the first such case in Korea. (Ann Dermatol 22(4) 468 ∼471, 2010)

show abstract

“…Nevertheless, the disease may be widespread, with papules scattered over the face, limbs and, rarely, the trunk. The distribution is often symmetrical [22] and there is no apparent racial or ethnic predominance [3], The clinical course of the disorder is unpredictable but usually chron ic, although spontaneous resolution has been reported [23].…”

Section: Discussionmentioning

confidence: 99%

“…In EPS the elastotic fibers seem to act as an irritating material and become enveloped by claw-like pseudoepitheliomatous downgrowths, before being extruded through the epidermis [3].…”

Section: Discussionmentioning

confidence: 99%

“…More than 100 patients with EPS have been reported in the literature and in onefourth of the cases EPS occurred in associa tion with several types of hereditary disor ders such as Ehlers-Danlos syndrome, pseu doxanthoma elasticum, Marfan's syndrome, osteogenesis imperfecta, and mongolism [3]. Single cases have been reported associated with Rothmund-Thomson syndrome, acrogeria, systemic sclerosis, Kyrle's disease [4] and aortic rupture [5].…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation