Future human service providers will interact with homeless persons in health, mental health, and social service practice contexts. This study investigated the perceptions of students enrolled in social work courses who are pursuing degrees in human service programs toward older and younger female and male homeless individuals. Respondents (N = 207) were given one of four vignettes in which a character was identified as an older male, a younger male, an older female, or a younger female who was frequently seen near an interstate highway, talking to him/herself and appearing unkempt, thin, and frail. Most respondents perceived the vignette character as mentally ill, neglectful of health, likely to have HIV, tuberculosis, hepatitis A and/or hepatitis B and/or hepatitis C, likely to experience suicidal thoughts/ideation, and to have head lice/scabies/body lice. Older men were more likely to be perceived as military veterans with a history of mental illness and substance abuse. Older women were least likely to be perceived as having a history of substance abuse or using a handout to purchase ethanol. Older women were perceived to be homeless because they could not afford other living accommodations. A general linear model revealed significant differences in 7 of 41 items that respondents answered based on the gender and age of the vignette characters. These perceptual differences between male and female homeless persons will require additional investigation.The attitudes of social workers and other human service professionals toward homeless persons may impact intervention, service delivery, and willingness to work with these populations. There is little literature investigating the perceptions of people preparing for human service careers toward older and younger homeless women and men and whether perceptual differences ex-).ist toward homeless persons based on the age and gender of the homeless person. It was hypothesized that there would be differences in how older and younger homeless men and women are viewed.Because homelessness occurs throughout the lifespan and to consider whether age and gender impacted beliefs and perceptions, four 261