Elderly Japanese Standard Data of Echocardiography; From J-LONG study

Seo, Yoshihiro; Ishizu, Tomoko; Ieda, Masaki; Ohte, Nobuyuki; Investigators, J-Long Study

doi:10.1007/s12574-020-00469-7

Cited by 9 publications

(1 citation statement)

References 17 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…With the advancement of age, echocardiographic indicators of atrial function, such as the left atrial expansion index, peak systolic strain, strain rate, and left atrial emptying fraction (LAEF) decrease and left atrial stiffness index and atrial conduction time (PA-TDI) increase (Abou et al, 2017;Olsen et al, 2021). Color Doppler imaging studies have determined that the average early-diastolic velocity (EDV) decreases and the late-diastolic velocity (LDV) increases as age progresses, leading to the decline of EDV/LDV ratio, an indicator of cardiac diastolic function (Seo et al, 2020). Cardiac magnetic resonance (CMR) is a specialized application of MRI which produces high-quality images of cardiovascular system to assess cardiac function and structure.…”

Section: Imaging Traitsmentioning

confidence: 99%

Biomarkers of aging

Bao

Cao

Chen

et al. 2023

Sci. China Life Sci.

153

View full text Add to dashboard Cite

Aging biomarkers are a combination of biological parameters to (i) assess age-related changes, (ii) track the physiological aging process, and (iii) predict the transition into a pathological status. Although a broad spectrum of aging biomarkers has been developed, their potential uses and limitations remain poorly characterized. An immediate goal of biomarkers is to help us answer the following three fundamental questions in aging research: How old are we? Why do we get old? And how can we age slower? This review aims to address this need. Here, we summarize our current knowledge of biomarkers developed for cellular, organ, and organismal levels of aging, comprising six pillars: physiological characteristics, medical imaging, histological features, cellular alterations, molecular changes, and secretory factors. To fulfill all these requisites, we propose that aging biomarkers should qualify for being specific, systemic, and clinically relevant. Supporting Information The supporting information is available online at 10.1007/s11427-023-2305-0. The supporting materials are published as submitted, without typesetting or editing. The responsibility for scientific accuracy and content remains entirely with the authors.

show abstract

Section: Imaging Traitsmentioning

confidence: 99%