2014
DOI: 10.1016/j.ejca.2013.12.026
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Elderly patients with colorectal cancer: Treatment modalities and survival in France. National data from the ThInDiT cohort study

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Cited by 78 publications
(56 citation statements)
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“…2 Although a pooled analysis of clinical trials 3 has suggested a benefit from ACT for the elderly, these patients may differ substantially from elderly patients in the general population. Several cohort studies have shown reasonable tolerance for ACT 4 and evidence of a survival benefit from ACT 3,[5][6][7][8][9] in the elderly; however, there remains significant variability in the utilization of ACT, 4,10,11 with age being a strong determinant of whether patients receive [10][11][12] or prematurely discontinue treatment. 13 Although several large population-based studies from the United States [5][6][7][8][9] have evaluated the effectiveness of ACT in the elderly, with 1 exception, these studies have used the Surveillance, Epidemiology, and End Results (SEER)-Medicare database and, therefore, are unable to provide comparative measures of effectiveness between elderly and nonelderly patients.…”
Section: Introductionmentioning
confidence: 99%
“…2 Although a pooled analysis of clinical trials 3 has suggested a benefit from ACT for the elderly, these patients may differ substantially from elderly patients in the general population. Several cohort studies have shown reasonable tolerance for ACT 4 and evidence of a survival benefit from ACT 3,[5][6][7][8][9] in the elderly; however, there remains significant variability in the utilization of ACT, 4,10,11 with age being a strong determinant of whether patients receive [10][11][12] or prematurely discontinue treatment. 13 Although several large population-based studies from the United States [5][6][7][8][9] have evaluated the effectiveness of ACT in the elderly, with 1 exception, these studies have used the Surveillance, Epidemiology, and End Results (SEER)-Medicare database and, therefore, are unable to provide comparative measures of effectiveness between elderly and nonelderly patients.…”
Section: Introductionmentioning
confidence: 99%
“…In a recently published French study, surgery was performed in 80% of cases in both younger and older age groups (Doat et al . ).…”
Section: Discussionmentioning
confidence: 97%
“…In the elderly, anticancer surgery was prescribed in more than 81% of localised cancer cases, a figure that differs only marginally from younger individuals. In a recently published French study, surgery was performed in 80% of cases in both younger and older age groups (Doat et al 2014).…”
Section: Colorectal Cancermentioning
confidence: 99%
“…[10,16]. Mais si la survie nette, ou quantité de vie, est un élément indiscutable en cancérologie, l'accent est mis aussi de plus en plus sur la qualité de vie, tout particulièrement chez les personnes âgées.…”
Section: Tableau IVunclassified