Elderly Patients with Schizophrenia and Depression: Diagnosis and Treatment

Felmet, Kandi; Zisook, Sidney; Kasckow, John

doi:10.3371/csrp.4.4.4

Cited by 36 publications

(37 citation statements)

References 152 publications

(152 reference statements)

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“…Based on DSM-IV classification, negative symptoms of schizophrenia include affective flattening, alogia, avolition and anhedonia [41]. There is thus a great overlap between symptoms of depression and negative symptoms of schizophrenia [48].…”

Section: Differential Diagnosis Of Depression In Schizophreniamentioning

confidence: 99%

Forms of antipsychotic therapy: improved individual outcomes under personalised treatment of schizophrenia focused on depression

Babinkostova¹,

Stefanovski²

2011

EPMA Journal

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Depressive symptoms are common in schizophrenia and they can occur during any phase of the disorder. Early diagnosis, adequate differential diagnosis and promptly initiated interventions have been shown to reduce further deterioration of illness and to improve patients’ quality of life. Common psychiatric rating scales for early detection of depressive symptoms in schizophrenia are Calgary Depression Scale for Schizophrenia and Hamilton Depression Rating Scale, but the most appropriate assessment instrument today regarding this topic is Calgary Depression Scale for Schizophrenia. Treatment of depression in schizophrenia consists of a combination of pharmacologic and psychosocial approach. Atypical antipsychotics have advantages over typical in reducing depressive symptoms in the context of schizophrenia. Most of the studies referred that clozapine, olanzapine, quetiapine and risperidone have an antidepressant spectrum of activity in patients with schizophrenia. Antidepressant augmentation of antipsychotic treatment in schizophrenic patients with depressive symptoms improves depressive symptomatology, particularly SSRI and SNRI augmentation.

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Section: Differential Diagnosis Of Depression In Schizophreniamentioning

confidence: 99%

Forms of antipsychotic therapy: improved individual outcomes under personalised treatment of schizophrenia focused on depression

Babinkostova¹,

Stefanovski²

2011

EPMA Journal

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“…Clozapine and olanzapine, as well as typical antipsychotics, should be avoided in cases of diabetes, dyslipidemia, or obesity. If the therapeutic choice forces the use of one of these drugs, some anthropometrical and metabolic parameters (ie, glycemia, blood pressure, abdominal fat, body mass index) should be closely monitored 46. In particular for schizophrenia, regardless of the specific treatment planned, both the individual variability in the response to the antipsychotic drugs and the effects of age itself on disease progression must be taken into account.…”

Section: Resultsmentioning

confidence: 99%

Use of atypical antipsychotics in the elderly: a clinical review

Gareri¹,

Segura-Garcìa²,

Manfredi³

et al. 2014

CIA

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The use of atypical antipsychotic drugs in the elderly has become wider and wider in recent years; in fact, these agents have novel receptor binding profiles, good efficacy with regard to negative symptoms, and reduced extrapyramidal symptoms. However, in recent years, the use of both conventional and atypical antipsychotics has been widely debated for concerns about their safety in elderly patients affected with dementia and the possible risks for stroke and sudden death. A MEDLINE search was made using the words elderly, atypical antipsychotics, use, schizophrenia, psychosis, mood disorders, dementia, behavioral disorders, and adverse events. Some personal studies were also considered. This paper reports the receptor binding profiles and the main mechanism of action of these drugs, together with their main use in psychiatry and the possible adverse events in elderly people.

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“…As the literature continues to grow regarding the differentiation between normal aging and mental health disorders (i.e. Menninger, 2002;Felmet et al, 2011), they may also become more involved in mental health services and substance abuse treatment. Hopefully, students will be able to use their interactions with partners and their issues and experiences as they encounter older adults in future practice.…”

Section: Discussionmentioning

confidence: 98%

‘Hearing the Real Stories about the Issues at Hand’: Politically Active Elders Engage Bachelor in Social Work (BSW) Students in Influencing Social Policy

Tower

Hash

2013

Social Work Education

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This article focuses on the successes and challenges experienced by a social work program offering experiential learning opportunities to bachelor in social work (BSW) students. As part of the BSW Experiential Learning (BEL) Program, policy students collaborated with politically active older adults to develop compelling letters to the editor of a newspaper and influential letters to state-level legislators concerning policies impacting older adults. Using a two-year quasi-experimental design, one section of the course paired students with older adults while the other section served as the control group. Although no significant differences were found in influencing student interest in working with older adults, students paired with older adults showed greater confidence in and learning of the content. Lessons learned from this experience and implications for future implementation will be detailed.

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Elderly Patients with Schizophrenia and Depression: Diagnosis and Treatment

Cited by 36 publications

References 152 publications

Forms of antipsychotic therapy: improved individual outcomes under personalised treatment of schizophrenia focused on depression

Forms of antipsychotic therapy: improved individual outcomes under personalised treatment of schizophrenia focused on depression

Use of atypical antipsychotics in the elderly: a clinical review

‘Hearing the Real Stories about the Issues at Hand’: Politically Active Elders Engage Bachelor in Social Work (BSW) Students in Influencing Social Policy

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