Elecrospun nanofibers: The versatile platform as a drug delivery system in healthcare

Bishnoi, Ananya; Tiwari, Raj Kumar; Chanda, Silpi; Ajmal, Gufran; Bonde, Gunjan Vasant

doi:10.1016/j.jddst.2023.105127

Cited by 2 publications

(1 citation statement)

References 91 publications

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“…These applications are made possible by the unusual physical properties of nanofibrous materials, which mimic the extracellular matrix . Due to its versatility in producing a variety of biomimetic nanofibers from different polymers and inorganic materials, in addition to its relative ease of use and adaptability, the electrospinning technique has attracted much interest in the fields of tissue engineering and drug delivery systems . The critical biomedical applications of the electrospun nanofibers have been reviewed here.…”

Section: Biomedical Applicationsmentioning

confidence: 99%

Electrospun Polymeric Nanofibers: Current Trends in Synthesis, Surface Modification, and Biomedical Applications

Yessuf,

Bahri,

Kassa

et al. 2024

ACS Appl. Bio Mater.

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Electrospun polymeric nanofibers are essential in various fields for various applications because of their unique properties. Their features are similar to extracellular matrices, which suggests them for applications in healthcare fields, such as antimicrobials, tissue engineering, drug delivery, wound healing, bone regeneration, and biosensors. This review focuses on the synthesis of electrospun polymeric nanofibers, their surface modification, and their biomedical applications. Nanofibers can be fabricated from both natural and synthetic polymers and their composites. Even though they mimic extracellular matrices, their surface features (physicochemical characteristics) are not always capable of fulfilling the purpose of the target application. Therefore, they need to be improved via surface modification techniques. Both needle-based and needleless electrospinning are thoroughly discussed. Various techniques and setups employed in each method are also reviewed. Furthermore, pre-and postspinning modification approaches for electrospun nanofibers, including instrument design and the modification features for targeted biomedical applications, are also extensively discussed. In this way, the remarkable potential of electrospun polymeric nanofibers can be highlighted to reveal future research directions in this dynamic field.

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Section: Biomedical Applicationsmentioning

confidence: 99%

Electrospun Polymeric Nanofibers: Current Trends in Synthesis, Surface Modification, and Biomedical Applications

Yessuf,

Bahri,

Kassa

et al. 2024

ACS Appl. Bio Mater.

View full text Add to dashboard Cite

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State‐of‐the‐Art Synthesis of Porous Polymer Materials and Their Several Fantastic Biomedical Applications: a Review

Ahmed,

Loukanov,

Tsai

2024

Adv Healthcare Materials

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Porous polymers, including hydrogels, covalent organic frameworks (COFs), and hyper crosslinked polymers (HCPs), have become essential in biomedical research for their tunable pore architectures, large surface areas, and functional versatility. This review provides a comprehensive overview of their classification and updated synthesis mechanisms, such as 3D printing, electrospinning, and molecular imprinting. Their pivotal roles in drug delivery, tissue engineering, wound healing, and photodynamic/photothermal therapies, focusing on how pore size, distribution, and architecture impact drug release, cellular interactions, and therapeutic outcomes, are explored. Key challenges, including biocompatibility, mechanical strength, controlled degradation, and scalability, are critically assessed alongside emerging strategies to enhance clinical potential. Finally, recent challenges and future perspectives, emphasizing the broader biomedical applications of porous polymers, are addressed. This work provides valuable insights for advancing next‐generation biomedical innovations through these materials.

show abstract

Elecrospun nanofibers: The versatile platform as a drug delivery system in healthcare

Cited by 2 publications

References 91 publications

Electrospun Polymeric Nanofibers: Current Trends in Synthesis, Surface Modification, and Biomedical Applications

Electrospun Polymeric Nanofibers: Current Trends in Synthesis, Surface Modification, and Biomedical Applications

State‐of‐the‐Art Synthesis of Porous Polymer Materials and Their Several Fantastic Biomedical Applications: a Review

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