Elective induction of labour and expectant management in late-term pregnancy: A prospective cohort study alongside the INDEX randomised controlled trial

Cost-effectiveness analysis of induction of labour at 41 weeks and expectant management until 42 weeks in low risk women (INDEX trial)

“…The recently published prospective cohort study alongside the INDEX trial shows less composite adverse as well as less severe adverse perinatal outcomes in both the induction of labour (CAPO 1.1 %; SAPO 0.3 %) and expectant management (CAPO 1.9 %; SAPO 1.0 %) groups compared to the trial [7] . This could indicate selection bias in trial, which is likely when we compare baseline characteristics with higher BMI and anxiety and lower SES and quality of life in the trial population.…”

“…For composite severe adverse perinatal outcome risks were 0.4 % after induction versus 1.3 % after expectant management (RR 0.3; 95 % CI 0.11–1.03) [3] . The INDEX cohort study — alongside the INDEX trial — found also lower incidences of adverse perinatal outcomes (IOL 1.1 % versus EM 1.9 %; adjRR 0.56; 95 % CI 0.17–1.79)) and severe adverse perinatal outcome (IOL 0.3 % versus EM 1.0 %; adjRR 0.39; 95 % CI 0.05–2.88)) than in the trial [7] .…”