Elective late fetal karyotyping

Fisk, Nicholas M.; Fordham, Karen; Abramsky, Lenore

doi:10.1111/j.1471-0528.1996.tb09775.x

Cited by 20 publications

(15 citation statements)

References 7 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Only five studies [9][10][11][12][13] have been published, but in only one [8] the indication was fetal karyotyping. In the other studies amniocentesis was performed to assess fetal lung maturity [10][11][12][13] and thus they would not be appropriate for comparison with our study.…”

Section: Discussionmentioning

confidence: 99%

“…An excess risk of fetal loss of around 0.6-1% is commonly reported [7] . Fisk et al [8] and Shalev et al [9] were the first to describe late amniocentesis as an alternative for women who are unwilling to accept the risks of early fetal karyotyping in a small series of 3 [8] and 14 [9] women. However, the risks of amniocentesis for fetal karyotyping, performed in the third-trimester, are poorly described [8][9][10][11][12][13][14] .…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Fear of Pregnancy Loss and Fetal Karyotyping: A Place for Third-Trimester Amniocentesis?

et al. 2007

View full text Add to dashboard Cite

Objective: To assess the complications of third-trimester amniocentesis for fetal karyotyping in women unwilling to accept the fetal loss risks of second-trimester amniocentesis. Methods: Retrospective study of singleton pregnancies that underwent a third-trimester amniocentesis for karyotyping. 150 complete charts between 1998 and 2005 were reviewed. Results: The indications were: isolated abnormal second-trimester biochemical markers (n = 57), isolated maternal age >38 years (n = 46), integrated risk (maternal age, first-trimester nuchal translucency, second-trimester maternal serum markers) >1/250 (n = 22), history of chromosomal abnormality (n = 17) or maternal choice (n = 8). The median maternal age and gestational age at sampling were: 40 years (23–48), 32.4 weeks (29.7–37.1). Median interval between amniocentesis, definitive result of amniocentesis, and delivery were 14 days (7–42), and 49 days (10–67) respectively. There were no abnormal karyotypes and no termination of pregnancy. Six women out of 150 (4%) had spontaneous labor before 36 weeks (2% after 36 weeks). Conclusion: The risk of spontaneous labor before 37 weeks after late amniocentesis is 4% (2% before 36 weeks). This technique provides a late but safe reassurance to women who are unwilling to accept the risks of earlier fetal karyotyping. This is of interest to countries such as France where legislation permits late termination of pregnancy.

show abstract

Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Fear of Pregnancy Loss and Fetal Karyotyping: A Place for Third-Trimester Amniocentesis?

et al. 2007

View full text Add to dashboard Cite

show abstract

“…However, it is clearly a complex issue for parents and health care professionals in European countries such as France [13] and the UK, which currently permit third trimester termination for non-lethal abnormalities with varying degrees of mental handicap. Indeed some authorities [14] have recently advocated deferral of invasive testing into the third trimester to avoid procedurerelated losses of chromosomally normal fetuses.…”

Section: The Importance Of Invasive Prenatal Diagnosis In Iugrmentioning

confidence: 99%

Diagnosis and Management of IUGR

Kingdom¹,

Smith²

2000

Intrauterine Growth Restriction

View full text Add to dashboard Cite

“…Les risques ainsi que les complications des amniocentèses du deuxième trimestre ont bien été rapporté, dans la littérature, avec un taux de perte foetale situé à 0,6-1 % [6,7]. Fisk et al [8] ainsi que Shalev et al [9] ont décrit, pour la première fois, les amniocentèses tardives comme une alternative pour les patientes refusant d'accepter le risque de fausse couche spontanée dues aux amniocentèses du deuxième trimestre, dans des séries de trois [8] et 14 [9] patientes. Cependant, les risques et les complications de ces amniocentèses tardives restent peu étudiés [8,13].…”

Section: Introductionunclassified