1975
DOI: 10.1159/000136937
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Electrical and Mechanical Activity of the Isolated Canine Stomach Perfused with Homologous, <i>in vitro</i>, Oxygenated Blood

Abstract: Electrical and mechanical activity was recorded from six totally isolated canine stomachs perfused with homologous blood oxygenated in vitro. Reactions to electrical vagal stimulation to cholinergic drugs and to pentagastrin were recorded. Electrical control activity, electrical response activity and mechanical response of isolated stomachs, observed in this in vitro system, were identical to those found in canine-isolated stomachs perfused with cross-circulated blood of living animals. It appears that when a … Show more

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Cited by 3 publications
(4 citation statements)
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“…The mechanism of ECA and ERA has been described (16,20) and will not be discussed here. Suffice it to mention that recordings of ECA, ERA and contractions, obtained from isolated stomachs, perfused with homologous blood, are similar to those obtained under in vivo conditions (11,12,16,20,21).…”
Section: Methodsmentioning
confidence: 60%
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“…The mechanism of ECA and ERA has been described (16,20) and will not be discussed here. Suffice it to mention that recordings of ECA, ERA and contractions, obtained from isolated stomachs, perfused with homologous blood, are similar to those obtained under in vivo conditions (11,12,16,20,21).…”
Section: Methodsmentioning
confidence: 60%
“…Preser vation of the functional integrity of the Lataijet nerve was confirmed by the normal response to electrical stimulation of this nerve. The normal response to pentagastrin (11)(12)(13)16), suggested the functional integrity of the intramural plexus (16). Pentagastrin probably exerts its stimulating action on smooth muscle by releasing acetylcholine from the intramural gastric plexus (11,16).…”
Section: Discussionmentioning
confidence: 99%
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