Electrical and Physical Sensors for Biomedical Implants

Kassanos, Panagiotis; Anastasova, Salzitsa; Yang, Guang‐Zhong

doi:10.1007/978-3-319-69748-2_3

Cited by 9 publications

(9 citation statements)

References 280 publications

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“…at low frequencies, demonstrating a capacitive behavior (C membr ). Thus, at low frequencies the extracellular space is probed (R extra ) [23], [24]. With an increasing frequency, membrane capacitive impedance is progressively diminished and increasingly more current flows through the membrane and into the intracellular space (R intra ).…”

Section: Electrical Properties Of Biological Mattermentioning

confidence: 99%

“…With increasing frequency, this is reduced in distinct steps in identifiable regions in the spectral characteristics, known as dispersion regions. There are four generally defined dispersion regions, α, β, γ and δ, as illustrated in Fig, 1(e) [22], [23], [26], [27]. The median value between two adjacent dispersion regions, i.e., between α and β, is called the characteristic frequency.…”

Section: Electrical Properties Of Biological Mattermentioning

confidence: 99%

“…Between the β and γ regions, the δ region is related with protein molecules and other organic macromolecules, as well as intracellular structures, such as organelle membranes (e.g. mitochondria) [22], [23], [26], [27].…”

Section: Electrical Properties Of Biological Mattermentioning

confidence: 99%

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Bioimpedance Sensors: A Tutorial

Kassanos

2021

IEEE Sensors J.

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Electrical bioimpedance entails the measurement of the electrical properties of tissues as a function of frequency. It is thus a spectroscopic technique. It has been applied in a plethora of biomedical applications for diagnostic and monitoring purposes. In this tutorial, the basics of electrical bioimpedance sensor design will be discussed. The electrode/electrolyte interface is thoroughly described, as well as methods for its modelling with equivalent circuits and computational tools. The design optimization and modelling of bipolar and tetrapolar bioimpedance sensors is presented in detail, based on the sensitivity theorem. Analytical and numerical modelling approaches for electric field simulations based on conformal mapping, point electrode approximations and the finite element method (FEM) are also elaborated. Finally, current trends on bioimpedance sensors are discussed followed by an overview of instrumentation methods for bioimpedance measurements, covering aspects of voltage signal excitations, current sources, voltage measurement front-end topologies and methods for computing the electrical impedance.

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Section: Electrical Properties Of Biological Mattermentioning

confidence: 99%

Section: Electrical Properties Of Biological Mattermentioning

confidence: 99%

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Bioimpedance Sensors: A Tutorial

Kassanos

2021

IEEE Sensors J.

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“…Implementation of bioimpedance sensing in Lab-on-Chip based technology for point-of-care (PoC) and need-of-care (NoC) devices [364] opens new perspectives to prevent of epidemic spread of infectious diseases in developing countries, and environmental and social disasters, everywhere. New implantable sensors can be designed as well on the bases of bioimpedance sensing [365]. The biosensors can detect cell nutrients such as glucose, metabolites such as lactate, cell density and pH in biological processes, but the field of research is open to new parameters and substances.…”

Section: Future Challenges Of Bioimpedancementioning

confidence: 99%

Fundamentals, Recent Advances, and Future Challenges in Bioimpedance Devices for Healthcare Applications

2019

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This work develops a thorough review of bioimpedance systems for healthcare applications. The basis and fundamentals of bioimpedance measurements are described covering issues ranging from the hardware diagrams to the configurations and designs of the electrodes and from the mathematical models that describe the frequency behavior of the bioimpedance to the sources of noise and artifacts. Bioimpedance applications such as body composition assessment, impedance cardiography (ICG), transthoracic impedance pneumography, electrical impedance tomography (EIT), and skin conductance are described and analyzed. A breakdown of recent advances and future challenges of bioimpedance is also performed, addressing topics such as transducers for biosensors and Lab-on-Chip technology, measurements in implantable systems, characterization of new parameters and substances, and novel bioimpedance applications.

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“…However, in many cases it is either not technically feasible or uneconomic to monitor the components or parts of interest with dedicated sensors [8,9,10]. For instance, it is not possible to incorporate sensor technology into a part of interest-such as i.e., a seal-due to, for instance, technical reasons or unreasonable expenses.…”

Section: Introductionmentioning

confidence: 99%

Holistic System-Analytics as an Alternative to Isolated Sensor Technology: A Condition Monitoring Use Case

Martin¹,

Kühl²

2019

Proceedings of the Annual Hawaii International Conference on System Sciences

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Sensor technology has become increasingly important (e.g., Industry 4.0, IoT). Large numbers of machines and products are equipped with sensors to constantly monitor their condition. Usually, the condition of an entire system is inferred through sensors in parts of the system by means of a multiplicity of methods and techniques. This so-called condition monitoring can thus reduce the downtime costs of a machine through improved maintenance scheduling. However, for small components as well as relatively inexpensive or immutable parts of a machine, sometimes it is not possible or uneconomical to embed sensors. We propose a system-oriented concept of how to monitor individual components of a complex technical system without including additional sensor technology. By using already existing sensors from the environment combined with machine learning techniques, we are able to infer the condition of a system component, without actually observing it. In consequence condition monitoring or additional services based on the component's behavior can be developed without overcoming the challenges of sensor implementation.

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Electrical and Physical Sensors for Biomedical Implants

Cited by 9 publications

References 280 publications

Bioimpedance Sensors: A Tutorial

Bioimpedance Sensors: A Tutorial

Fundamentals, Recent Advances, and Future Challenges in Bioimpedance Devices for Healthcare Applications

Holistic System-Analytics as an Alternative to Isolated Sensor Technology: A Condition Monitoring Use Case

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