Electrical Conductances of Dilute Aqueous Solutions of Sodium Penicillin G, Potassium Penicillin G, and Potassium Penicillin V in the 278.15−313.15 K Temperature Range

Bešter‐Rogač, Marija; Bončina, Matjaž; Apelblat, Yoram; Apelblat, Alexander

doi:10.1021/jp0748819

Cited by 7 publications

(8 citation statements)

References 52 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The z + and z -designate the charge number of the cation and anion, respectively, and and are the molar conductivities of the cation and anion in Sm 2 /mol, respectively at infinite dilution. The molar conductivity was determined using the measured electrolytic conductivity, , in S/m, which depends primarily on the type of electrolyte and the molar concentration of the solution in kmol/m 3 . Equation (2) shows the given formula for the evaluation of molar conductivity, , in S·m 2 /mol [8] The molar conductivities of the cation and anion at infinite dilution are determined using the Kohlrausch's law of the Independent Migration of Ions which states that the molar conductivity of an electrolyte at infinite dilution can be expressed in terms of the sum of contribution from the cation and anion of antibiotic in dilute solution as presented in Eqn.…”

Section: Diffusion Coefficient Determinationmentioning

confidence: 99%

“…In order to predict the fate and transport in the environment, physicochemical properties of different substances are taken into account. There are several parameters considered such as molecular weight, aqueous solubility, chemical concentration, diffusion coefficient, Henry's law constant, boiling point and vapor pressure [3]. The study mainly focuses on the determination of diffusion coefficient of antibiotics, which can be helpful for future studies in detecting and removing antibiotics in wastewater.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Determination of diffusion coefficients of various livestock antibiotics in water at infinite dilution

et al. 2017

View full text Add to dashboard Cite

Abstract. The fate of antibiotics entering the environment raised concerns on the possible effect of antimicrobial resistance bacteria. Prediction of the fate and transport of these particles are needed to be determined, significantly the diffusion coefficient of antibiotic in water at infinite dilution. A systematic determination of diffusion coefficient of antibiotic in water at infinite dilution of five different kinds of livestock antibiotics namely: Amtyl, Ciprotyl, Doxylak Forte, Trisullak, and Vetracin Gold in the 293.15 to 313.15 K temperature range are reported through the use of the method involving the electrolytic conductivity measurements. A continuous stirred tank reactor is utilized to measure the electrolytic conductivities of the considered systems. These conductivities are correlated by using the Nernst-Haskell equation to determine the infinite dilution diffusion coefficient. Determined diffusion coefficients are based on the assumption that in dilute solution, these antibiotics behave as strong electrolyte from which H + cation dissociate from the antibiotic's anion.

show abstract

Section: Diffusion Coefficient Determinationmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Determination of diffusion coefficients of various livestock antibiotics in water at infinite dilution

et al. 2017

View full text Add to dashboard Cite

show abstract

“…From the form of conductivity curves it is clear that paraben sodium salts deviate from the expected behavior of a strong 1:1 electrolyte (Figure ). Considering that the paraben salts (RPBONa) come from weak organic acids and when dissolved in water they partially hydrolyze, we can assume the following set of reactions: .25ex2ex RPBONa → Na + + RPBO − RPBO − + normalH + ⇌ RPBOH normalH 2 normalO ⇌ normalH + + OH − The mass-action equations for these reactions can be written as .25ex2ex K = a normalH + a RPB normalO − a RPBOH = [ H + ] [ RPB O − ] f normalH + f RPB normalO − [ RPBOH ] f RPBOH = [ H…”

Section: Resultsmentioning

confidence: 99%

Dissociation Constants of Parabens and Limiting Conductances of Their Ions in Water

2012

Self Cite

View full text Add to dashboard Cite

Precise measurements of electrical conductivities of methylparaben, ethylparaben, propylparaben, and butylparaben sodium salts in dilute aqueous solutions were performed from 278.15 to 313.15 K in 5 K intervals. Experimental conductivity data were analyzed applying the Quint-Viallard conductivity equations by taking into account the salt hydrolysis in aqueous solutions. These evaluations yield the limiting conductances of paraben anions and the dissociation constants of the investigated parabens in water. From temperature dependence of dissociation constants, the thermodynamic functions associated with the dissociation process were estimated. It was discovered that the contributions of enthalpy and entropy to the Gibbs free energy are quite similar. The Walden products of paraben anions in water are independent of temperature, indicating that the hydrodynamic radii are not significantly affected by temperature.

show abstract

“…Apelblat and his colleagues first proposed a modified Apelblat model, − and this formula (), which accurately describes the relationship between the solubility of the solute in the solution system and the system temperature, is as follows: …”

Section: Theoretical Aspectsmentioning

confidence: 99%

Determination and Analysis of Solubility of 4-[2-(N-Methylcarbamyl)-4-pyridyloxy]aniline in Ten Pure Solvents and Three Binary Solvent Mixtures at Different Temperatures (T = 278.15–323.15 K)

et al. 2021

View full text Add to dashboard Cite

In this study, the data on solid–liquid equilibrium of 4-[2-(N-methylcarbamyl)-4-pyridyloxy]aniline were studied by the gravimetric method. The solubility of 4-[2-(N-methylcarbamyl)-4-pyridyloxy]aniline was measured in 10 pure solvents (ethyl acetate, tetrahydrofuran, acetonitrile, dichloromethane, acetone, methanol, acetylacetone, n-propanol, n-butanol, and water) and three binary solvent mixtures (water + tetrahydrofuran, acetone + n-butanol, and ethyl acetate + n-propanol) in the temperature range of 278.15 to 323.15 K under atmospheric pressure. The experimental results show that the solubility of 4-[2-(N-methylcarbamyl)-4-pyridyloxy]aniline in the abovementioned solvents increases with the increase of temperature. Among the 10 pure solvents, ethyl acetate has the highest solubility. The improved Apelblat model, Buchowski–Ksiazaczak λh model, Redlich–Kister (CNIBS/R-K) model, and Jouyban–Acree model are used for nonlinear fitting of experimental data, and the KAT-LSER model is also used to study the relationship between the solubility of 4-[2-(N-methylcarbamyl)-4-pyridyloxy]aniline in pure solvents and the interaction between solvent and solute molecules. The physical and chemical information of 4-[2-(N-methylcarbamyl)-4-pyridyloxy]aniline provided in this report may help its extraction/separation, recrystallization, purification, and formulation development.

show abstract

Electrical Conductances of Dilute Aqueous Solutions of Sodium Penicillin G, Potassium Penicillin G, and Potassium Penicillin V in the 278.15−313.15 K Temperature Range

Cited by 7 publications

References 52 publications

Determination of diffusion coefficients of various livestock antibiotics in water at infinite dilution

Determination of diffusion coefficients of various livestock antibiotics in water at infinite dilution

Dissociation Constants of Parabens and Limiting Conductances of Their Ions in Water

Determination and Analysis of Solubility of 4-[2-(N-Methylcarbamyl)-4-pyridyloxy]aniline in Ten Pure Solvents and Three Binary Solvent Mixtures at Different Temperatures (T = 278.15–323.15 K)

Contact Info

Product

Resources

About