Electrical stimulation: a novel therapeutic strategy to heal biological wounds

Preetam, Subham; Ghosh, Arka; Mishra, Richa; Pandey, Arunima; Roy, Debanjan Singha; Rustagi, Sarvesh; Malik, Sumira

doi:10.1039/d4ra04258a

RSC Adv.

2024

DOI: 10.1039/d4ra04258a

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Electrical stimulation: a novel therapeutic strategy to heal biological wounds

Subham Preetam,

Arka Ghosh,

Richa Mishra

et al.

Abstract: Electrical stimulation (ES) has emerged as a powerful therapeutic modality for enhancing biological wound healing.

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Aberrances of the Wound Healing Process: A Review

Fernandez-Guarino,

Naharro-Rodriguez,

Bacci

2024

Cosmetics

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Wound healing is a complex biological process that can lead to chronic wounds, keloids, and hypertrophic scars when disrupted. Chronic wounds result from a prolonged inflammatory phase and impaired re-epithelialization. Keloids are characterized by excessive collagen deposition beyond the original wound boundaries, driven by persistent inflammation and fibroblast hyperactivity. Hypertrophic scars, on the other hand, are confined to the wound edges and are caused by an imbalance in collagen synthesis and degradation, typically resolving over time. The therapeutic approach to wound healing impairment involves a range of strategies, including non-invasive (which focus on supporting the natural healing process), minimally invasive, and aggressive interventions (such as surgical approach, often reserved for severe or refractory cases). Emerging therapies, including stem cell treatments and botulinum toxin injections, offer new hope for improving outcomes in patients with wound healing impairments. This review highlights the distinct mechanisms underlying chronic wounds, keloids, and hypertrophic scars and discusses their respective therapeutic approaches, focusing on both established and emerging therapies. Understanding these mechanisms is crucial for optimizing treatment strategies and improving patient outcomes.

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Aberrances of the Wound Healing Process: A Review

Fernandez-Guarino,

Naharro-Rodriguez,

Bacci

2024

Cosmetics

View full text Add to dashboard Cite

show abstract

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Electrical stimulation: a novel therapeutic strategy to heal biological wounds

Abstract: Electrical stimulation (ES) has emerged as a powerful therapeutic modality for enhancing biological wound healing.

Cited by 1 publication

References 196 publications

Aberrances of the Wound Healing Process: A Review

Aberrances of the Wound Healing Process: A Review

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