Electrical stimulation of auditory and somatosensory cortices for treatment of tinnitus and pain

Ridder, Dirk De; Mulder, Gert De; Menovsky, Tomas; Sunaert, Stefan; Kovacs, Silvia

doi:10.1016/s0079-6123(07)66036-1

Cited by 106 publications

(59 citation statements)

References 35 publications

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“…Direct manipulation of the S1 cortex modulates the neuronal activity evoked by innocuous and noxious peripheral stimulation in downstream brain areas associated with pain signaling including the thalamus and anterior cingulate cortex (9,13). Such S1 cortex manipulation can temporarily relieve neuropathic pain in humans and animals (14)(15)(16). This suggests that the S1 cortex might play a role as a "central processing unit" within the brain networks that mediate and/or sustain chronic neuropathic pain.…”

Section: Introductionmentioning

confidence: 99%

Cortical astrocytes rewire somatosensory cortical circuits for peripheral neuropathic pain

Kim

Hayashi

Ishikawa

et al. 2016

Journal of Clinical Investigation

161

183

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Section: Introductionmentioning

confidence: 99%

Cortical astrocytes rewire somatosensory cortical circuits for peripheral neuropathic pain

Kim

Hayashi

Ishikawa

et al. 2016

Journal of Clinical Investigation

161

183

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“…It has been stated that there are clinical, pathophysiological and treatment analogies between phantom pain and phantom sound (De Ridder et al, 2007a;Moller, 1997Moller, , 2000Tonndorf, 1987). The anterior cingulate cortex (Mobascher et al, 2009) and the insula (Brooks et al, 2005), which interact with the prefrontal cortex and amygdala play a central role in emotion-cognitive aspects of pain processing (Craig, 2003;Peyron et al, 2000).…”

Section: Introductionmentioning

confidence: 99%

The neural correlates of tinnitus-related distress

et al. 2010

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Tinnitus is an auditory phantom percept with a tone, hissing, or buzzing sound in the absence of any objective physical sound source. About 6% to 25% of the affected people report interference with their lives as tinnitus causes a considerable amount of distress. However, the underlying neurophysiological mechanism for the development of tinnitus-related distress remains not well understood. Hence we focus on the cortical and subcortical source differences in resting-state EEG between tinnitus patients with different grades of distress using continuous scalp EEG recordings and Low Resolution Electromagnetic Tomography (LORETA). Results show more synchronized alpha activity in the tinnitus patients with a serious amount of distress with peaks localized to various emotion-related areas. These areas include subcallosal anterior cingulate cortex, the insula, parahippocampal area and amygdala. In addition, less alpha synchronized activity was found in the posterior cingulate cortex, precuneus and DLPFC. A comparison between the tinnitus group with distress and the Nova Tech EEG (NTE) normative database demonstrated increased synchronized alpha and beta activity and less synchronized delta and theta activity in the dorsal anterior cingulate cortex in tinnitus patients with distress. It is interesting that the areas found show some overlap with the emotional component of the pain matrix and the distress related areas in asthmatic dyspnea. Unpleasantness of pain activates the anterior cingulate and prefrontal cortices, amygdala, and insula. As such, it might be that distress is related to alpha and beta activity in the dorsal anterior cingulate cortex, the amount of distress perceived to an alpha network consisting of the amygdala-anterior cingulate cortex-insula-parahippocampal area.

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“…(3) The abnormal neuronal activity can be modulated by neuronavigated TMS resulting in transient tinnitus reduction [12]. (4) If TMS can transiently suppress the tinnitus, electrical stimulation through an electrode implanted on the same area can provide permanent tinnitus suppression [10][11][12]20].…”

Section: Introductionmentioning

confidence: 99%

Multitarget surgical neuromodulation: Combined C2 and auditory cortex implantation for tinnitus

Ridder

Vanneste

2015

Neuroscience Letters

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Electrical stimulation of auditory and somatosensory cortices for treatment of tinnitus and pain

Cited by 106 publications

References 35 publications

Cortical astrocytes rewire somatosensory cortical circuits for peripheral neuropathic pain

Cortical astrocytes rewire somatosensory cortical circuits for peripheral neuropathic pain

The neural correlates of tinnitus-related distress

Multitarget surgical neuromodulation: Combined C2 and auditory cortex implantation for tinnitus

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