Electrically generated nitric oxide from air: a safe and economical treatment for pulmonary hypertension

Yu, Binglan; Zapol, Warren M.

doi:10.1007/s00134-019-05756-1

Cited by 3 publications

(2 citation statements)

References 17 publications

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“…However, an electrical generator that generates NO from air has been developed recently which may make inhaled NO more affordable and accessible, especially in under resourced settings where cylinder NO gas is not easily available 29 . Such developing technologies may have a significant impact on the feasibility and financial benefit of non-invasive NO use in a variety of patient population.…”

Section: Discussionmentioning

confidence: 99%

Feasibility of non-invasive nitric oxide gas inhalation to prevent endotracheal intubation in patients with acute hypoxemic respiratory failure: A single-centre experience

et al. 2021

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Section: Discussionmentioning

confidence: 99%

Feasibility of non-invasive nitric oxide gas inhalation to prevent endotracheal intubation in patients with acute hypoxemic respiratory failure: A single-centre experience

et al. 2021

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“…It is important that ambient nitrogen dioxide and NO levels are monitored and maintained within safe limits. A major barrier precluding the increased use NO appears to be the delivery cost.However, an electrical generator that generates NO from air has been developed recently which may make inhaled NO more affordable and accessible, especially in under resourced settings where cylinder NO gas is not easily available29 . Such developing technologies may have a significant impact on the feasibility and financial benefit of non-invasive NO use in a variety of patient population.Non-invasive NO inhalation may have a potential role in the current pandemic.…”

mentioning

confidence: 99%

Feasibility of non-invasive nitric oxide inhalation in acute hypoxic respiratory failure: potential role during the COVID-19 pandemic

Shekar

Varkey

Cornmell

et al. 2020

Preprint

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Acute hypoxemic respiratory failure (ARF) is characterized by both lower arterial oxygen and carbon dioxide tensions in the blood. First line treatment for ARF includes oxygen therapy,intially admininstered non invasively using nasal prongs, high flow nasal cannulae or masks. Invasive mechancial ventilation (IMV) is usually reserved for patients who are unable to maintain their airway, those with worsening hypoxemia, or those who develop respiratory muscle fatigue and consequent hypercapnia. Inhaled nitric oxide (iNO) gas is known to improve oxygenation in patients with ARF by manipulating ventilation-perfusion matching. Addition of iNO may potentially alleviate the need for IMV in selected patients. This article demonstrates the feasibility of this technique based on our experience of patients with hypoxemic ARF. This technique may also be considered for patients with hypoxic ARF in setting of COVID-19.

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Nitric oxide: Clinical applications in critically ill patients

et al. 2022

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Electrically generated nitric oxide from air: a safe and economical treatment for pulmonary hypertension

Cited by 3 publications

References 17 publications

Feasibility of non-invasive nitric oxide gas inhalation to prevent endotracheal intubation in patients with acute hypoxemic respiratory failure: A single-centre experience

Feasibility of non-invasive nitric oxide gas inhalation to prevent endotracheal intubation in patients with acute hypoxemic respiratory failure: A single-centre experience

Feasibility of non-invasive nitric oxide inhalation in acute hypoxic respiratory failure: potential role during the COVID-19 pandemic

Nitric oxide: Clinical applications in critically ill patients

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