This paper presents a dual-polarized crossed-dipole antenna with high isolation and widebeam radiation. The antenna comprises two orthogonal printed dipoles with single-ended and differential feeds, which are collocated on a square ground plane. The single-ended feed dipole is built on the peripheral sides of a two-layer substrate, and it is fed by a Γ-shaped stripline sandwiched between the substrate layers. The differential-feed dipole is built on a single-layer substrate, i.e., the differential feed with a Π-shaped microstrip-line, and the dipole arms are printed on the top-side and back-side of the substrate, respectively. The high isolation feature is achieved by exploiting the symmetry of the design with one pair of differential feeds. The beamwidth is significantly broadened by incorporating parasitic monopole elements while keeping the design symmetrical. A realization of the design concept for the 5G NR n78 band (3.3-3.8 GHz) has been optimized, fabricated, and tested. The measured results demonstrate an impedance bandwidth of 28.6% (3.0-4.0 GHz) and port-to-port isolation of > 40 dB. Furthermore, the antenna achieves a peak half-power beamwidth of 150 • /168 • in the E/H planes and a cross-polarization level of < −30 dB at the broadside direction. These features make the proposed antenna a good candidate for the 5G and in-band full-duplex applications.